ΔFosB accumulation in hippocampal granule cells drives cFos pattern separation during spatial learning
In mice, reactivation of neurons that express cFos during fear conditioning induces a behavioural response. Here the authors show that cFos expression in mouse dentate gyrus shifts every day to different neurons, even during highly consistent spatial navigation, and suggest this clock-like selection...
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Bibliographic Details
Main Authors: |
Paul J. Lamothe-Molina,
Andreas Franzelin,
Lennart Beck,
Dong Li,
Lea Auksutat,
Tim Fieblinger,
Laura Laprell,
Joachim Alhbeck,
Christine E. Gee,
Matthias Kneussel,
Andreas K. Engel,
Claus C. Hilgetag,
Fabio Morellini,
Thomas G. Oertner |
Format: | Article
|
Language: | English |
Published: |
Nature Portfolio
2022-10-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-022-33947-w
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