LOV2-based photoactivatable CaMKII and its application to single synapses: Local Optogenetics

LOV2-based photoactivatable CaMKII and its application to single synapses: Local Optogenetics

Optogenetic techniques offer a high spatiotemporal resolution to manipulate cellular activity. For instance, Channelrhodopsin-2 with global light illumination is the most widely used to control neuronal activity at the cellular level. However, the cellular scale is much larger than the diffraction l...

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Bibliographic Details
Main Authors: Yutaro Nagasawa, Hiromi H. Ueda, Haruka Kawabata, Hideji Murakoshi
Format: Article
Language:English
Published: The Biophysical Society of Japan 2023-06-01
Series:Biophysics and Physicobiology
Subjects:
lov2
photoactivatable camkii (pacamkii)
2-photon excitation
dendritic spine
excitatory neuron
Online Access:https://doi.org/10.2142/biophysico.bppb-v20.0027

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