Farnesoid X Receptor Activation Stimulates Organic Cations Transport in Human Renal Proximal Tubular Cells

Farnesoid X Receptor Activation Stimulates Organic Cations Transport in Human Renal Proximal Tubular Cells

Farnesoid X receptor (FXR) is a ligand-activated transcription factor highly expressed in the liver and kidneys. Activation of FXR decreases organic cation transporter (OCT) 1-mediated clearance of organic cation compounds in hepatocytes. The present study investigated FXR regulation of renal cleara...

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Bibliographic Details
Main Authors:	Teerasak Wongwan, Varanuj Chatsudthipong, Sunhapas Soodvilai
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Series:	International Journal of Molecular Sciences
Subjects:	Nuclear receptor renal excretion kidney drug transporters bile acids
Online Access:	https://www.mdpi.com/1422-0067/21/17/6078

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