Folate Conjugated Polyethylene Glycol Probe for Tumor-Targeted Drug Delivery of 5-Fluorouracil

Folate Conjugated Polyethylene Glycol Probe for Tumor-Targeted Drug Delivery of 5-Fluorouracil

A targeted delivery system is primarily intended to carry a potent anticancer drug to specific tumor sites within the bodily tissues. In the present study, a carrier system has been designed using folic acid (FA), bis-amine polyethylene glycol (PEG), and an anticancer drug, 5-fluorouracil (5-FU). FA...

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Bibliographic Details
Main Authors: Shabnam Sarwar, Muhammad Abdul Qadir, Rima D. Alharthy, Mahmood Ahmed, Saghir Ahmad, Michiel Vanmeert, Muhammad Usman Mirza, Abdul Hameed
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
folic acid
vector
HeLa cell
hepatoma mice
molecular dynamics simulations
Online Access:https://www.mdpi.com/1420-3049/27/6/1780

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