Highly Mimetic Ex Vivo Lung‐Cancer Spheroid‐Based Physiological Model for Clinical Precision Therapeutics

Highly Mimetic Ex Vivo Lung‐Cancer Spheroid‐Based Physiological Model for Clinical Precision Therapeutics

Abstract Lung cancer remains a major health problem despite the considerable research into prevention and treatment methods. Through a deeper understanding of tumors, patient‐specific ex vivo spheroid models with high specificity can be used to accurately investigate the cause, metastasis, and treat...

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Bibliographic Details
Main Authors: Ming‐You Shie, Hsin‐Yuan Fang, Kai‐Wen Kan, Chia‐Che Ho, Chih‐Yen Tu, Pei‐Chih Lee, Po‐Ren Hsueh, Chia‐Hung Chen, Alvin Kai‐Xing Lee, Ni Tien, Jian‐Xun Chen, Yu‐Cheng Shen, Jan‐Gowth Chang, Yu‐Fang Shen, Ting‐Ju Lin, Ben Wang, Mien‐Chie Hung, Der‐Yang Cho, Yi‐Wen Chen
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Advanced Science
Subjects:
decellularized extracellular matrix
lung spheroid model
precision medicine
tumor microenvironment
Online Access:https://doi.org/10.1002/advs.202206603

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