Pigmental form of the lichen planus: clinical-morphological parallels

In article are described results of own supervision over patients pigmental by the form lichen ruber planus (LP) which is the atypical form of defeat of a skin and mucous membranes. Modern methods of research have allowed the author to approach from new positions to studying pigmental LP and to defi...

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Main Author: Svyatenko T.V.
Format: Article
Language:Russian
Published: Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy 2008-01-01
Series:Морфологія
Subjects:
Online Access:http://www.morphology.dp.ua/_pub/MORPHO-2008-02-04/08stvkgp.pdf
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author Svyatenko T.V.
author_facet Svyatenko T.V.
author_sort Svyatenko T.V.
collection DOAJ
description In article are described results of own supervision over patients pigmental by the form lichen ruber planus (LP) which is the atypical form of defeat of a skin and mucous membranes. Modern methods of research have allowed the author to approach from new positions to studying pigmental LP and to define a role tissue changes in pathogenesis of dermatosis. By the author it is studied clinical, pathomorphology and immunohistochemical features pigmental forms LP. Under supervision was 10 patients with pigmental form LP. The analysis of results of the lead morphological researches the amazed skin has revealed infringement of processes keratinisation, dystrophic and proliferation changes in epidermis, inflammatory changes in derma, presence except lymphohistiocytes elements, and numerous melanophags with the considerable maintenance of a pigment in cytoplasm. At carrying out immunohistochemical researches by the author it is obtained following data: Significant amount CD68 + cages macrophagals a number in a zone expressed infiltrations of derma, typical granularical cytoplasmatic character of colouring. On the basis of the lead researches it is possible to approve, that diagnostics pigmental forms LP which differs clinical polymorphism, that should be based on complex studying macro-and microscopic picture of defeat in view of specific features dermatosis, that will allow different to approach to questions of purpose of treatment.
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spelling doaj.art-353ed87599ce4ba8a8d6c6781a9eb3732022-12-22T03:21:57ZrusMinistry of Health of Ukraine. Dnipropetrovsk Medical AcademyМорфологія1997-96652008-01-0124510Pigmental form of the lichen planus: clinical-morphological parallelsSvyatenko T.V.In article are described results of own supervision over patients pigmental by the form lichen ruber planus (LP) which is the atypical form of defeat of a skin and mucous membranes. Modern methods of research have allowed the author to approach from new positions to studying pigmental LP and to define a role tissue changes in pathogenesis of dermatosis. By the author it is studied clinical, pathomorphology and immunohistochemical features pigmental forms LP. Under supervision was 10 patients with pigmental form LP. The analysis of results of the lead morphological researches the amazed skin has revealed infringement of processes keratinisation, dystrophic and proliferation changes in epidermis, inflammatory changes in derma, presence except lymphohistiocytes elements, and numerous melanophags with the considerable maintenance of a pigment in cytoplasm. At carrying out immunohistochemical researches by the author it is obtained following data: Significant amount CD68 + cages macrophagals a number in a zone expressed infiltrations of derma, typical granularical cytoplasmatic character of colouring. On the basis of the lead researches it is possible to approve, that diagnostics pigmental forms LP which differs clinical polymorphism, that should be based on complex studying macro-and microscopic picture of defeat in view of specific features dermatosis, that will allow different to approach to questions of purpose of treatment.http://www.morphology.dp.ua/_pub/MORPHO-2008-02-04/08stvkgp.pdfpigmental form of the lichen planushistological pictureimmunohistochemical features
spellingShingle Svyatenko T.V.
Pigmental form of the lichen planus: clinical-morphological parallels
Морфологія
pigmental form of the lichen planus
histological picture
immunohistochemical features
title Pigmental form of the lichen planus: clinical-morphological parallels
title_full Pigmental form of the lichen planus: clinical-morphological parallels
title_fullStr Pigmental form of the lichen planus: clinical-morphological parallels
title_full_unstemmed Pigmental form of the lichen planus: clinical-morphological parallels
title_short Pigmental form of the lichen planus: clinical-morphological parallels
title_sort pigmental form of the lichen planus clinical morphological parallels
topic pigmental form of the lichen planus
histological picture
immunohistochemical features
url http://www.morphology.dp.ua/_pub/MORPHO-2008-02-04/08stvkgp.pdf
work_keys_str_mv AT svyatenkotv pigmentalformofthelichenplanusclinicalmorphologicalparallels