Immunotherapy for Visceral Leishmaniasis: Ability of Factors Produced during Anti-leishmania Responses of Skin Test Positive Adults to Inhibit Peripheral Blood Mononuclear Cell Activities Associated with Visceral Leishmaniasis

Immunotherapy for Visceral Leishmaniasis: Ability of Factors Produced during Anti-leishmania Responses of Skin Test Positive Adults to Inhibit Peripheral Blood Mononuclear Cell Activities Associated with Visceral Leishmaniasis

The course of human Leishmania chagasi infections appears to be determined by the balance between type 1 (T1) CD4+ and CD8+ T suppressor (Ts) cell activities. Skin test positive adults living in hyperendemic areas who have no history of visceral leishmaniasis (VL) have T1 CD4+ T cell immunodominant...

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Bibliographic Details
Main Author: Holaday Bettie J
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 1999-01-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
leishmaniasis
CD8+ T suppressor (Ts)
immunotherapy
interleukin (IL)-10
IL-12
antigens
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000100013

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