The Effect of Palm Pollen and Black Seed Pollen on Male Sex Hormones and Sperm Quality: A Single-Blind, Placebo-Controlled Clinical Trial Study
Background: Nowadays, using medicinal properties is a good alternative for infertility treatment to use them is increasing in the world. The aim of this study was to determine the effects of Herbal oral capsules included palm pollen extract (DPP) and Nigella Sativa extract (NS) on sex hormones in ad...
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| Format: | Article |
| Language: | English |
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Royan Institute (ACECR), Tehran
2023-01-01
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| Series: | International Journal of Fertility and Sterility |
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| Online Access: | https://www.ijfs.ir/article_252746_c9ca9ac3965138dc4236ba87ee3d36fc.pdf |
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| author | Ali Hajb Zeynab Salehpour Roghayyeh Aghaei Aida Najafian Masoumeh Mahmoodi Masoomeh Latifi Soghra Fallahi |
| author_facet | Ali Hajb Zeynab Salehpour Roghayyeh Aghaei Aida Najafian Masoumeh Mahmoodi Masoomeh Latifi Soghra Fallahi |
| author_sort | Ali Hajb |
| collection | DOAJ |
| description | Background: Nowadays, using medicinal properties is a good alternative for infertility treatment to use them is increasing in the world. The aim of this study was to determine the effects of Herbal oral capsules included palm pollen extract (DPP) and Nigella Sativa extract (NS) on sex hormones in adult infertile men.Materials and Methods: In this a single-blind, placebo-controlled clinical trial study, a total of 62 infertile men between 22 and 42 years of age were randomly selected and tested for sex hormones and prolactin. Thirty people in the case group received two 500 mg/kg capsules on a daily basis containing an herbal composition of palm pollen extract (350 mg) and black seed powder extract (250 mg) and the 20 in the control group received a placebo in the morning and at night for 3 months. The herbal composition capsules were manufactured by the Golbadistan Company. At the end of the three -month period, blood and semen tests were performed before and after the intervention in the case group that was compared with the control group. Hormonal assays were performed by Immunoradiometric Assay (IRMA) method. The data entered SPSS statistical software and the level of significance was set at P≤0.05.Results: The spermiogram test results showed significant changes in the sperm count, progressive motility and rapid progressivity of the case group at the end of a quarterly period after consuming plant composition except for morphology (P=0.001, P=0.001, P=0.02, P=0.23). In addition, in the case group, the concentration of testosterone, follicle stimulating hormone (FSH), luteinizing hormone (LH) was significantly increased compared to the control group (P=0.000, P=0.004, P=0.012).Conclusion: It seems that taking one 500 mg/kg capsule of DPP and NS extract can significantly increase sperm parameters and testosterone (registration number: IRCT2015020120895N1). |
| first_indexed | 2024-04-11T01:08:21Z |
| format | Article |
| id | doaj.art-354303c68c2e4bf28f24bdc4f1b2a821 |
| institution | Directory Open Access Journal |
| issn | 2008-076X 2008-0778 |
| language | English |
| last_indexed | 2024-04-11T01:08:21Z |
| publishDate | 2023-01-01 |
| publisher | Royan Institute (ACECR), Tehran |
| record_format | Article |
| series | International Journal of Fertility and Sterility |
| spelling | doaj.art-354303c68c2e4bf28f24bdc4f1b2a8212023-01-04T10:54:14ZengRoyan Institute (ACECR), TehranInternational Journal of Fertility and Sterility2008-076X2008-07782023-01-01171757910.22074/ijfs.2022.548477.1259252746The Effect of Palm Pollen and Black Seed Pollen on Male Sex Hormones and Sperm Quality: A Single-Blind, Placebo-Controlled Clinical Trial StudyAli Hajb0Zeynab Salehpour1Roghayyeh Aghaei2Aida Najafian3Masoumeh Mahmoodi4Masoomeh Latifi5Soghra Fallahi6Golestan Navy Hospital, Tehran, IranMedicinal Plants Research Center, Yaasuj University of Medical Sciences, Yasuj, IranDepartment of Marine Chemistry, Faculty of Marine Science, Chabahar Maritime University, Chabahar, IranDepartment of Endocrinology and Infertility, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, IranFertility and Infertility Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, IranFertility and Infertility Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, IranBackground: Nowadays, using medicinal properties is a good alternative for infertility treatment to use them is increasing in the world. The aim of this study was to determine the effects of Herbal oral capsules included palm pollen extract (DPP) and Nigella Sativa extract (NS) on sex hormones in adult infertile men.Materials and Methods: In this a single-blind, placebo-controlled clinical trial study, a total of 62 infertile men between 22 and 42 years of age were randomly selected and tested for sex hormones and prolactin. Thirty people in the case group received two 500 mg/kg capsules on a daily basis containing an herbal composition of palm pollen extract (350 mg) and black seed powder extract (250 mg) and the 20 in the control group received a placebo in the morning and at night for 3 months. The herbal composition capsules were manufactured by the Golbadistan Company. At the end of the three -month period, blood and semen tests were performed before and after the intervention in the case group that was compared with the control group. Hormonal assays were performed by Immunoradiometric Assay (IRMA) method. The data entered SPSS statistical software and the level of significance was set at P≤0.05.Results: The spermiogram test results showed significant changes in the sperm count, progressive motility and rapid progressivity of the case group at the end of a quarterly period after consuming plant composition except for morphology (P=0.001, P=0.001, P=0.02, P=0.23). In addition, in the case group, the concentration of testosterone, follicle stimulating hormone (FSH), luteinizing hormone (LH) was significantly increased compared to the control group (P=0.000, P=0.004, P=0.012).Conclusion: It seems that taking one 500 mg/kg capsule of DPP and NS extract can significantly increase sperm parameters and testosterone (registration number: IRCT2015020120895N1).https://www.ijfs.ir/article_252746_c9ca9ac3965138dc4236ba87ee3d36fc.pdfinfertile menprolactinsex hormones |
| spellingShingle | Ali Hajb Zeynab Salehpour Roghayyeh Aghaei Aida Najafian Masoumeh Mahmoodi Masoomeh Latifi Soghra Fallahi The Effect of Palm Pollen and Black Seed Pollen on Male Sex Hormones and Sperm Quality: A Single-Blind, Placebo-Controlled Clinical Trial Study International Journal of Fertility and Sterility infertile men prolactin sex hormones |
| title | The Effect of Palm Pollen and Black Seed Pollen on Male Sex Hormones and Sperm Quality: A Single-Blind, Placebo-Controlled Clinical Trial Study |
| title_full | The Effect of Palm Pollen and Black Seed Pollen on Male Sex Hormones and Sperm Quality: A Single-Blind, Placebo-Controlled Clinical Trial Study |
| title_fullStr | The Effect of Palm Pollen and Black Seed Pollen on Male Sex Hormones and Sperm Quality: A Single-Blind, Placebo-Controlled Clinical Trial Study |
| title_full_unstemmed | The Effect of Palm Pollen and Black Seed Pollen on Male Sex Hormones and Sperm Quality: A Single-Blind, Placebo-Controlled Clinical Trial Study |
| title_short | The Effect of Palm Pollen and Black Seed Pollen on Male Sex Hormones and Sperm Quality: A Single-Blind, Placebo-Controlled Clinical Trial Study |
| title_sort | effect of palm pollen and black seed pollen on male sex hormones and sperm quality a single blind placebo controlled clinical trial study |
| topic | infertile men prolactin sex hormones |
| url | https://www.ijfs.ir/article_252746_c9ca9ac3965138dc4236ba87ee3d36fc.pdf |
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