GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway

GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway

Steroidal glycoalkaloids (SGAs) accumulate in solanaceous plants and contribute to plant defence but are toxic to humans. Here the authors show that the GAME9 transcription factor is a regulator of the SGA biosynthetic pathways providing a potential way to manipulate SGA levels in crops.

Bibliographic Details
Main Authors: Pablo D. Cárdenas, Prashant D. Sonawane, Jacob Pollier, Robin Vanden Bossche, Veena Dewangan, Efrat Weithorn, Lior Tal, Sagit Meir, Ilana Rogachev, Sergey Malitsky, Ashok P. Giri, Alain Goossens, Saul Burdman, Asaph Aharoni
Format: Article
Language:English
Published: Nature Portfolio 2016-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10654

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