Leukemia Inhibitory Factor Stimulates Primitive Endoderm Expansion in the Bovine Inner Cell Mass

Leukemia Inhibitory Factor Stimulates Primitive Endoderm Expansion in the Bovine Inner Cell Mass

Previous work determined that bovine interleukin-6 (IL6) increases inner cell mass (ICM), primitive endoderm (PE), and total cell number in in vitro produced (IVP) bovine blastocysts. Another IL6 family member, leukemia inhibitory factor (LIF), has the potential to produce the same effects of IL6 du...

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Bibliographic Details
Main Authors: Lydia K. Wooldridge, Alan D. Ealy
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Animal Science
Subjects:
embryo
blastocyst
primitive endoderm
interleukin-6
leukemia inhibitory factor
Online Access:https://www.frontiersin.org/articles/10.3389/fanim.2021.796489/full

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