Effects of Glucocorticoid Therapy on Sepsis Depend Both on the Dose of Steroids and on the Severity and Phase of the Animal Sepsis Model

Effects of Glucocorticoid Therapy on Sepsis Depend Both on the Dose of Steroids and on the Severity and Phase of the Animal Sepsis Model

Steroids are currently being used in sepsis, particularly in septic shock. However, clinical trials to date have shown contradictory results. This could be attributed to the different patient endotypes and steroid doses, which have also contributed to the inconclusive results. We investigated the ef...

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Bibliographic Details
Main Authors: Ye Jin Park, Min Ji Lee, Jinkun Bae, Jung Ho Lee, Han A Reum Lee, Sehwan Mun, Yun-seok Kim, Chang June Yune, Tae Nyoung Chung, Kyuseok Kim
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Life
Subjects:
sepsis
glucocorticoid
immunosuppression
cytokines
rats
Online Access:https://www.mdpi.com/2075-1729/12/3/421

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