A xCT role in tumour-associated ferroptosis shed light on novel therapeutic options

Solute carrier family 7 member 11 (SLC7A11; also known as xCT), a key component of the cystine/glutamate antiporter, is essential for the maintenance of cellular redox status and the regulation of tumor-associated ferroptosis. Accumulating evidence has demonstrated that xCT overexpression, resulting...

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Bibliographic Details
Main Authors: Daniela Criscuolo, Francesco Morra, Angela Celetti
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2022-10-01
Series:Exploration of Targeted Anti-tumor Therapy
Subjects:
Online Access:https://www.explorationpub.com/Journals/etat/Article/1002101

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