A Single Aptamer-Dependent Sandwich-Type Biosensor for the Colorimetric Detection of Cancer Cells via Direct Coordinately Binding of Bare Bimetallic Metal–Organic Framework-Based Nanozymes

A Single Aptamer-Dependent Sandwich-Type Biosensor for the Colorimetric Detection of Cancer Cells via Direct Coordinately Binding of Bare Bimetallic Metal–Organic Framework-Based Nanozymes

A typical colorimetric sandwich-type sensor relies on dual antibodies/aptamers to specifically visualize the targets. The requirement of dual antibodies/aptamers and low signal intensity inevitably increases the design difficulty and compromises the sensing sensitivity. In this work, a novel sandwic...

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Bibliographic Details
Main Authors: Yuhui Zhu, Xueting Fang, Xiaofei Lv, Meijun Lu, Hui Xu, Shengqiang Hu, Shulin Zhao, Fanggui Ye
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biosensors
Subjects:
metal–organic frameworks
sandwich-type
single aptamer
coordination bond
colorimetric detection
Online Access:https://www.mdpi.com/2079-6374/13/2/225

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