Accounting for long-range correlations in genome-wide simulations of large cohorts.
Coalescent simulations are widely used to examine the effects of evolution and demographic history on the genetic makeup of populations. Thanks to recent progress in algorithms and data structures, simulators such as the widely-used msprime now provide genome-wide simulations for millions of individ...
Main Authors: | Dominic Nelson, Jerome Kelleher, Aaron P Ragsdale, Claudia Moreau, Gil McVean, Simon Gravel |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-05-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1008619 |
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