Cytokines-Biogenesis and Their Role in Human Breast Milk and Determination
Cytokines play a huge role in many biological processes. Their production, release and interactions are subject to a very complex mechanism. Cytokines are produced by all types of cells, they function very differently and they are characterized by synergism in action, antagonism, and aggregation act...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-06-01
|
| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/12/6238 |
| _version_ | 1797530719715590144 |
|---|---|
| author | Anna Kiełbasa Renata Gadzała-Kopciuch Bogusław Buszewski |
| author_facet | Anna Kiełbasa Renata Gadzała-Kopciuch Bogusław Buszewski |
| author_sort | Anna Kiełbasa |
| collection | DOAJ |
| description | Cytokines play a huge role in many biological processes. Their production, release and interactions are subject to a very complex mechanism. Cytokines are produced by all types of cells, they function very differently and they are characterized by synergism in action, antagonism, and aggregation activity, opposing action of one cytokine, overlapping activity, induction of another cytokine, inhibition of cytokine synthesis at the mRNA level as well as autoregulation-stimulation or inhibition of own production. The predominance of pro-inflammatory cytokines leads to a systemic inflammatory response, and anti-inflammatory-to an anti-inflammatory response. They regulate the organism’s immune response and protect it against sudden disturbances in homeostasis. The synthesis and activity of cytokines are influenced by the central nervous system through the endocrine system (pituitary gland, adrenal glands). |
| first_indexed | 2024-03-10T10:33:02Z |
| format | Article |
| id | doaj.art-3555505fdfcf49ce95b2ceaae68a33cf |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T10:33:02Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-3555505fdfcf49ce95b2ceaae68a33cf2023-11-21T23:28:52ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-06-012212623810.3390/ijms22126238Cytokines-Biogenesis and Their Role in Human Breast Milk and DeterminationAnna Kiełbasa0Renata Gadzała-Kopciuch1Bogusław Buszewski2Department of Environmental Chemistry and Bioanalysis, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, ul. Gagarina 7, 87-100 Toruń, PolandDepartment of Environmental Chemistry and Bioanalysis, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, ul. Gagarina 7, 87-100 Toruń, PolandDepartment of Environmental Chemistry and Bioanalysis, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, ul. Gagarina 7, 87-100 Toruń, PolandCytokines play a huge role in many biological processes. Their production, release and interactions are subject to a very complex mechanism. Cytokines are produced by all types of cells, they function very differently and they are characterized by synergism in action, antagonism, and aggregation activity, opposing action of one cytokine, overlapping activity, induction of another cytokine, inhibition of cytokine synthesis at the mRNA level as well as autoregulation-stimulation or inhibition of own production. The predominance of pro-inflammatory cytokines leads to a systemic inflammatory response, and anti-inflammatory-to an anti-inflammatory response. They regulate the organism’s immune response and protect it against sudden disturbances in homeostasis. The synthesis and activity of cytokines are influenced by the central nervous system through the endocrine system (pituitary gland, adrenal glands).https://www.mdpi.com/1422-0067/22/12/6238cytokinesELISAfatty acidshuman breast milkMALDIpro- and anti-inflammatory properties |
| spellingShingle | Anna Kiełbasa Renata Gadzała-Kopciuch Bogusław Buszewski Cytokines-Biogenesis and Their Role in Human Breast Milk and Determination International Journal of Molecular Sciences cytokines ELISA fatty acids human breast milk MALDI pro- and anti-inflammatory properties |
| title | Cytokines-Biogenesis and Their Role in Human Breast Milk and Determination |
| title_full | Cytokines-Biogenesis and Their Role in Human Breast Milk and Determination |
| title_fullStr | Cytokines-Biogenesis and Their Role in Human Breast Milk and Determination |
| title_full_unstemmed | Cytokines-Biogenesis and Their Role in Human Breast Milk and Determination |
| title_short | Cytokines-Biogenesis and Their Role in Human Breast Milk and Determination |
| title_sort | cytokines biogenesis and their role in human breast milk and determination |
| topic | cytokines ELISA fatty acids human breast milk MALDI pro- and anti-inflammatory properties |
| url | https://www.mdpi.com/1422-0067/22/12/6238 |
| work_keys_str_mv | AT annakiełbasa cytokinesbiogenesisandtheirroleinhumanbreastmilkanddetermination AT renatagadzałakopciuch cytokinesbiogenesisandtheirroleinhumanbreastmilkanddetermination AT bogusławbuszewski cytokinesbiogenesisandtheirroleinhumanbreastmilkanddetermination |