Genetic and constitutional factors are major contributors to substantia nigra hyperechogenicity

Abstract Hyperechogenicity of substantia nigra (SNh) is a frequent finding in amyotrophic lateral sclerosis (ALS), Parkinson’s disease (PD) and other movement disorders (MD) patients, but its meaning is unclear. To ascertain the contribution of different factors to SNh area, we measured it in 108 AL...

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Bibliographic Details
Main Authors: Juan F. Vázquez-Costa, José I. Tembl, Victoria Fornés-Ferrer, Fernando Cardona, Lluis Morales-Caba, Gerardo Fortea, Jordi Pérez-Tur, Teresa Sevilla
Format: Article
Language:English
Published: Nature Portfolio 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07835-z