A systematic study of independently-tuned room-specific PBS beam model in a beam-matched multiroom proton therapy system
Abstract Background In the existing application of beam-matched multiroom proton therapy system, the model based on the commissioning data from the leading treatment room was used as the shared model. The purpose of this study is to investigate the ability of independently-tuned room-specific beam m...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-10-01
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| Series: | Radiation Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13014-021-01932-0 |
| _version_ | 1818843244875743232 |
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| author | Yu-Hua Huang Chunfeng Fang Tao Yang Lin Cao Gaolong Zhang Baolin Qu Yihang Zhang Zishen Wang Shouping Xu |
| author_facet | Yu-Hua Huang Chunfeng Fang Tao Yang Lin Cao Gaolong Zhang Baolin Qu Yihang Zhang Zishen Wang Shouping Xu |
| author_sort | Yu-Hua Huang |
| collection | DOAJ |
| description | Abstract Background In the existing application of beam-matched multiroom proton therapy system, the model based on the commissioning data from the leading treatment room was used as the shared model. The purpose of this study is to investigate the ability of independently-tuned room-specific beam models of beam-matched gantries to reproduce the agreement between gantries’ performance when considering the errors introduced by the modeling process. Methods Raw measurements of two gantries’ dosimetric characteristics were quantitatively compared to ensure their agreement after initially beam-matched. Two gantries’ beam model parameters, as well as the model-based computed dosimetric characteristics, were analyzed to study the introduced errors and gantries’ post-modeling consistency. We forced two gantries to share the same beam model. The model-sharing patient-specific quality assurance (QA) tasks were retrospectively performed with 36 cancer patients to study the clinical impact of beam model discrepancies. Results Intra-gantry comparisons demonstrate that the modeling process introduced the errors to a certain extent indeed, which made the model-based reproduced results deviate from the raw measurements. Among them, the deviation introduced to the IDD curves was generally larger than that to the beam spots during modeling. Cross-gantry comparisons show that, from the beam model perspective, the introduced deviations deteriorated the high agreement of the dosimetric characteristics originally shown between two beam-matched gantries, but the cross-gantry discrepancy was still within the clinically acceptable tolerance. In model-sharing patient-specific QA, for the particular gantry, the beam model usage for intensity-modulated proton therapy (IMPT) QA plan generation had no significant effect on the actual delivering performance. All reached a high level of 95.0% passing rate with a 3 mm/3% criterion. Conclusions It was preliminary recognized that among beam-matched gantries, the independently-tuned room-specific beam model from any gantry is reasonable to be chosen as the shared beam model without affecting the treatment efficacy. |
| first_indexed | 2024-12-19T04:54:48Z |
| format | Article |
| id | doaj.art-355a71f3efde42f5a1c602df90b4ff4f |
| institution | Directory Open Access Journal |
| issn | 1748-717X |
| language | English |
| last_indexed | 2024-12-19T04:54:48Z |
| publishDate | 2021-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Radiation Oncology |
| spelling | doaj.art-355a71f3efde42f5a1c602df90b4ff4f2022-12-21T20:35:16ZengBMCRadiation Oncology1748-717X2021-10-0116111010.1186/s13014-021-01932-0A systematic study of independently-tuned room-specific PBS beam model in a beam-matched multiroom proton therapy systemYu-Hua Huang0Chunfeng Fang1Tao Yang2Lin Cao3Gaolong Zhang4Baolin Qu5Yihang Zhang6Zishen Wang7Shouping Xu8Department of Radiation Oncology, The First Medical Center of PLA General HospitalDepartment of Radiation Oncology, Hebei Yizhou Cancer HospitalDepartment of Radiation Oncology, The First Medical Center of PLA General HospitalDepartment of Radiation Oncology, Hebei Yizhou Cancer HospitalSchool of Physics, Beihang UniversityDepartment of Radiation Oncology, The First Medical Center of PLA General HospitalSchool of Physics, Beihang UniversityDepartment of Radiation Oncology, Hebei Yizhou Cancer HospitalDepartment of Radiation Oncology, The First Medical Center of PLA General HospitalAbstract Background In the existing application of beam-matched multiroom proton therapy system, the model based on the commissioning data from the leading treatment room was used as the shared model. The purpose of this study is to investigate the ability of independently-tuned room-specific beam models of beam-matched gantries to reproduce the agreement between gantries’ performance when considering the errors introduced by the modeling process. Methods Raw measurements of two gantries’ dosimetric characteristics were quantitatively compared to ensure their agreement after initially beam-matched. Two gantries’ beam model parameters, as well as the model-based computed dosimetric characteristics, were analyzed to study the introduced errors and gantries’ post-modeling consistency. We forced two gantries to share the same beam model. The model-sharing patient-specific quality assurance (QA) tasks were retrospectively performed with 36 cancer patients to study the clinical impact of beam model discrepancies. Results Intra-gantry comparisons demonstrate that the modeling process introduced the errors to a certain extent indeed, which made the model-based reproduced results deviate from the raw measurements. Among them, the deviation introduced to the IDD curves was generally larger than that to the beam spots during modeling. Cross-gantry comparisons show that, from the beam model perspective, the introduced deviations deteriorated the high agreement of the dosimetric characteristics originally shown between two beam-matched gantries, but the cross-gantry discrepancy was still within the clinically acceptable tolerance. In model-sharing patient-specific QA, for the particular gantry, the beam model usage for intensity-modulated proton therapy (IMPT) QA plan generation had no significant effect on the actual delivering performance. All reached a high level of 95.0% passing rate with a 3 mm/3% criterion. Conclusions It was preliminary recognized that among beam-matched gantries, the independently-tuned room-specific beam model from any gantry is reasonable to be chosen as the shared beam model without affecting the treatment efficacy.https://doi.org/10.1186/s13014-021-01932-0Beam-matchingBeam analysisProton therapyPencil beam scanningMonte Carlo |
| spellingShingle | Yu-Hua Huang Chunfeng Fang Tao Yang Lin Cao Gaolong Zhang Baolin Qu Yihang Zhang Zishen Wang Shouping Xu A systematic study of independently-tuned room-specific PBS beam model in a beam-matched multiroom proton therapy system Radiation Oncology Beam-matching Beam analysis Proton therapy Pencil beam scanning Monte Carlo |
| title | A systematic study of independently-tuned room-specific PBS beam model in a beam-matched multiroom proton therapy system |
| title_full | A systematic study of independently-tuned room-specific PBS beam model in a beam-matched multiroom proton therapy system |
| title_fullStr | A systematic study of independently-tuned room-specific PBS beam model in a beam-matched multiroom proton therapy system |
| title_full_unstemmed | A systematic study of independently-tuned room-specific PBS beam model in a beam-matched multiroom proton therapy system |
| title_short | A systematic study of independently-tuned room-specific PBS beam model in a beam-matched multiroom proton therapy system |
| title_sort | systematic study of independently tuned room specific pbs beam model in a beam matched multiroom proton therapy system |
| topic | Beam-matching Beam analysis Proton therapy Pencil beam scanning Monte Carlo |
| url | https://doi.org/10.1186/s13014-021-01932-0 |
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