Revisiting corneal topography for the diagnosis of keratoconus: use of Rabinowitz's KISA% index

Mohammad Reza Sedghipour, Afshin Lotfi Sadigh, Behzad Fallahi MotlaghDepartment of Ophthalmology, Tabriz University of Medical Sciences, Tabriz, IranBackground: Numerous videokeratographic methods are used in the diagnosis of keratoconus.The purpose of this study was to compare the sensitivity and s...

Full description

Bibliographic Details
Main Authors: Sedghipour MR, Sadigh AL, Motlagh BF
Format: Article
Language:English
Published: Dove Medical Press 2012-01-01
Series:Clinical Ophthalmology
Online Access:http://www.dovepress.com/revisiting-corneal-topography-for-the-diagnosis-of-keratoconus-use-of--a9141
_version_ 1818428288300744704
author Sedghipour MR
Sadigh AL
Motlagh BF
author_facet Sedghipour MR
Sadigh AL
Motlagh BF
author_sort Sedghipour MR
collection DOAJ
description Mohammad Reza Sedghipour, Afshin Lotfi Sadigh, Behzad Fallahi MotlaghDepartment of Ophthalmology, Tabriz University of Medical Sciences, Tabriz, IranBackground: Numerous videokeratographic methods are used in the diagnosis of keratoconus.The purpose of this study was to compare the sensitivity and specificity of the KISA% index with the keratometry (K) value, inferior-superior (I-S) value, relative skewing of the steepest radial axes (SRAX), and keratometric astigmatism (AST) indices in 25 patients presenting with bilateral keratoconus.Methods: Twenty-five patients presenting with bilateral keratoconus were enrolled. Fifty eyes from 25 healthy individuals without corneal abnormalities were used as controls. The clinical diagnosis of keratoconus was made by observation of scissors reflex at retinoscopy and characteristic slit lamp findings. Corneal topographic analysis was performed in each eye to calculate the K value, I-S value, AST, and SRAX indices.Results: The keratoconus percentage index (KISA%) was significantly more sensitive and specific than the other indices examined. Furthermore, it was significantly better at predicting positive and negative results than the other indices included in the study.Conclusion: The current research suggests that KISA% could be used to detect/diagnose keratoconus but further studies are required to confirm the specificity and sensitivity of KISA% for the detection of early-stage disease and keratoconus suspects.Keywords: cornea, keratoconus, KISA% index
first_indexed 2024-12-14T14:59:14Z
format Article
id doaj.art-355b9c43ddad470bb4b047cef00c0a05
institution Directory Open Access Journal
issn 1177-5467
1177-5483
language English
last_indexed 2024-12-14T14:59:14Z
publishDate 2012-01-01
publisher Dove Medical Press
record_format Article
series Clinical Ophthalmology
spelling doaj.art-355b9c43ddad470bb4b047cef00c0a052022-12-21T22:56:54ZengDove Medical PressClinical Ophthalmology1177-54671177-54832012-01-012012default181184Revisiting corneal topography for the diagnosis of keratoconus: use of Rabinowitz's KISA% indexSedghipour MRSadigh ALMotlagh BFMohammad Reza Sedghipour, Afshin Lotfi Sadigh, Behzad Fallahi MotlaghDepartment of Ophthalmology, Tabriz University of Medical Sciences, Tabriz, IranBackground: Numerous videokeratographic methods are used in the diagnosis of keratoconus.The purpose of this study was to compare the sensitivity and specificity of the KISA% index with the keratometry (K) value, inferior-superior (I-S) value, relative skewing of the steepest radial axes (SRAX), and keratometric astigmatism (AST) indices in 25 patients presenting with bilateral keratoconus.Methods: Twenty-five patients presenting with bilateral keratoconus were enrolled. Fifty eyes from 25 healthy individuals without corneal abnormalities were used as controls. The clinical diagnosis of keratoconus was made by observation of scissors reflex at retinoscopy and characteristic slit lamp findings. Corneal topographic analysis was performed in each eye to calculate the K value, I-S value, AST, and SRAX indices.Results: The keratoconus percentage index (KISA%) was significantly more sensitive and specific than the other indices examined. Furthermore, it was significantly better at predicting positive and negative results than the other indices included in the study.Conclusion: The current research suggests that KISA% could be used to detect/diagnose keratoconus but further studies are required to confirm the specificity and sensitivity of KISA% for the detection of early-stage disease and keratoconus suspects.Keywords: cornea, keratoconus, KISA% indexhttp://www.dovepress.com/revisiting-corneal-topography-for-the-diagnosis-of-keratoconus-use-of--a9141
spellingShingle Sedghipour MR
Sadigh AL
Motlagh BF
Revisiting corneal topography for the diagnosis of keratoconus: use of Rabinowitz's KISA% index
Clinical Ophthalmology
title Revisiting corneal topography for the diagnosis of keratoconus: use of Rabinowitz's KISA% index
title_full Revisiting corneal topography for the diagnosis of keratoconus: use of Rabinowitz's KISA% index
title_fullStr Revisiting corneal topography for the diagnosis of keratoconus: use of Rabinowitz's KISA% index
title_full_unstemmed Revisiting corneal topography for the diagnosis of keratoconus: use of Rabinowitz's KISA% index
title_short Revisiting corneal topography for the diagnosis of keratoconus: use of Rabinowitz's KISA% index
title_sort revisiting corneal topography for the diagnosis of keratoconus use of rabinowitz amp 39 s kisa index
url http://www.dovepress.com/revisiting-corneal-topography-for-the-diagnosis-of-keratoconus-use-of--a9141
work_keys_str_mv AT sedghipourmr revisitingcornealtopographyforthediagnosisofkeratoconususeofrabinowitzamp39skisaindex
AT sadighal revisitingcornealtopographyforthediagnosisofkeratoconususeofrabinowitzamp39skisaindex
AT motlaghbf revisitingcornealtopographyforthediagnosisofkeratoconususeofrabinowitzamp39skisaindex