HMM-FRAME: accurate protein domain classification for metagenomic sequences containing frameshift errors
<p>Abstract</p> <p>Background</p> <p>Protein domain classification is an important step in metagenomic annotation. The state-of-the-art method for protein domain classification is profile HMM-based alignment. However, the relatively high rates of insertions and deletion...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-05-01
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| Series: | BMC Bioinformatics |
| Online Access: | http://www.biomedcentral.com/1471-2105/12/198 |