Nanoparticles: a challenging vehicle for neural stimulation
Neurostimulation represents a powerful and well-established tool for the treatment of several diseases affecting the central nervous system. Although effective in reducing the symptoms or the progression of brain disorders, the poor accessibility of the deepest areas of the brain currently hampers t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2016-03-01
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| Series: | Frontiers in Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00105/full |
| _version_ | 1819264539724611584 |
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| author | Elisabetta eColombo Paul eFeyen Maria Rosa Antognazza Guglielmo eLanzani Guglielmo eLanzani Fabio eBenfenati Fabio eBenfenati |
| author_facet | Elisabetta eColombo Paul eFeyen Maria Rosa Antognazza Guglielmo eLanzani Guglielmo eLanzani Fabio eBenfenati Fabio eBenfenati |
| author_sort | Elisabetta eColombo |
| collection | DOAJ |
| description | Neurostimulation represents a powerful and well-established tool for the treatment of several diseases affecting the central nervous system. Although effective in reducing the symptoms or the progression of brain disorders, the poor accessibility of the deepest areas of the brain currently hampers the possibility of a more specific and controlled therapeutic stimulation, depending on invasive surgical approaches and long-term stability and biocompatibility issues. The massive research of the last decades on nanomaterials and nanoscale devices favored the development of new tools to address the limitations of the available neurostimulation approaches. This mini-review focuses on the employment of nanoparticles for the modulation of the electrophysiological activity of neuronal networks and the related transduction mechanisms underlying the nanostructure-neuron interfaces. |
| first_indexed | 2024-12-23T20:31:06Z |
| format | Article |
| id | doaj.art-355eaa20987a43c4bbf01feb46368e79 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-12-23T20:31:06Z |
| publishDate | 2016-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-355eaa20987a43c4bbf01feb46368e792022-12-21T17:32:13ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2016-03-011010.3389/fnins.2016.00105183159Nanoparticles: a challenging vehicle for neural stimulationElisabetta eColombo0Paul eFeyen1Maria Rosa Antognazza2Guglielmo eLanzani3Guglielmo eLanzani4Fabio eBenfenati5Fabio eBenfenati6Istituto Italiano di Tecnologia (IIT)Istituto Italiano di Tecnologia (IIT)Istituto Italiano di Tecnologia (IIT)Istituto Italiano di Tecnologia (IIT)Politecnico di MilanoIstituto Italiano di Tecnologia (IIT)Università di GenovaNeurostimulation represents a powerful and well-established tool for the treatment of several diseases affecting the central nervous system. Although effective in reducing the symptoms or the progression of brain disorders, the poor accessibility of the deepest areas of the brain currently hampers the possibility of a more specific and controlled therapeutic stimulation, depending on invasive surgical approaches and long-term stability and biocompatibility issues. The massive research of the last decades on nanomaterials and nanoscale devices favored the development of new tools to address the limitations of the available neurostimulation approaches. This mini-review focuses on the employment of nanoparticles for the modulation of the electrophysiological activity of neuronal networks and the related transduction mechanisms underlying the nanostructure-neuron interfaces.http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00105/fullNeural ProstheticsnanoparticleneurostimulationNanobeadsneural activity modulation |
| spellingShingle | Elisabetta eColombo Paul eFeyen Maria Rosa Antognazza Guglielmo eLanzani Guglielmo eLanzani Fabio eBenfenati Fabio eBenfenati Nanoparticles: a challenging vehicle for neural stimulation Frontiers in Neuroscience Neural Prosthetics nanoparticle neurostimulation Nanobeads neural activity modulation |
| title | Nanoparticles: a challenging vehicle for neural stimulation |
| title_full | Nanoparticles: a challenging vehicle for neural stimulation |
| title_fullStr | Nanoparticles: a challenging vehicle for neural stimulation |
| title_full_unstemmed | Nanoparticles: a challenging vehicle for neural stimulation |
| title_short | Nanoparticles: a challenging vehicle for neural stimulation |
| title_sort | nanoparticles a challenging vehicle for neural stimulation |
| topic | Neural Prosthetics nanoparticle neurostimulation Nanobeads neural activity modulation |
| url | http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00105/full |
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