Parallel Analysis of Cystic Fibrosis Sputum and Saliva Reveals Overlapping Communities and an Opportunity for Sample Decontamination

Parallel Analysis of Cystic Fibrosis Sputum and Saliva Reveals Overlapping Communities and an Opportunity for Sample Decontamination

ABSTRACT Culture-independent studies of the cystic fibrosis (CF) airway microbiome typically rely on expectorated sputum to assess the microbial makeup of lower airways. These studies have revealed rich bacterial communities. There is often considerable overlap between taxa observed in sputum and th...

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Bibliographic Details
Main Authors: Junnan Lu, Lisa A. Carmody, Kristopher Opron, Richard H. Simon, Linda M. Kalikin, Lindsay J. Caverly, John J. LiPuma
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mSystems
Subjects:
microbiome
airway infection
microbial community dynamics
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00296-20

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