Design of Protease-Responsive Antifungal Liposomal Formulation Decorated with a Lipid-Modified Chitin-Binding Domain

Design of Protease-Responsive Antifungal Liposomal Formulation Decorated with a Lipid-Modified Chitin-Binding Domain

<i>Candida albicans</i> is a prevalent fungal pathogen that displays antibiotic resistance. The polyene antifungal amphotericin B (AmB) has been the gold standard because of its broad antifungal spectra, and its liposomal formulation, AmBisome, has been used widely and clinically in trea...

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Bibliographic Details
Main Authors: Hendra Saputra, Muhammad Safaat, Pugoh Santoso, Rie Wakabayashi, Masahiro Goto, Toki Taira, Noriho Kamiya
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
antifungal formulation
AmBisome
<i>C. albicans</i>
chitinase
lipid conjugation
Online Access:https://www.mdpi.com/1422-0067/25/7/3567

Internet

https://www.mdpi.com/1422-0067/25/7/3567

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