Graduate Student Literature Review: Developmental adaptations of immune function in calves and the influence of the intestinal microbiota in health and disease
ABSTRACT: This graduate student literature review provides an examination of the ontological adaptations of the calf's immune system and how the intestinal microbiota influences calf immune function in health and disease. Within dairy rearing systems, various nutritional and management factors...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-04-01
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| Series: | Journal of Dairy Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022030223007877 |
| _version_ | 1797249199005237248 |
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| author | L.R. Cangiano C. Villot L.L. Guan I.R. Ipharraguerre M.A. Steele |
| author_facet | L.R. Cangiano C. Villot L.L. Guan I.R. Ipharraguerre M.A. Steele |
| author_sort | L.R. Cangiano |
| collection | DOAJ |
| description | ABSTRACT: This graduate student literature review provides an examination of the ontological adaptations of the calf's immune system and how the intestinal microbiota influences calf immune function in health and disease. Within dairy rearing systems, various nutritional and management factors have emerged as critical determinants of development influencing multiple physiological axes in the calf. Furthermore, we discuss how multiple pre- and postnatal maternal factors influence the trajectory of immune development in favor of establishing regulatory networks to successfully cope with the new environment, while providing early immune protection via immune passive transfer from colostrum. Additionally, our review provides insights into the current understanding of how the intestinal microbiota contributes to the development of the intestinal and systemic immune system in calves. Lastly, we address potential concerns related to the use of prophylactic antimicrobials and waste milk, specifically examining their adverse effects on intestinal health and metabolic function. By examining these factors, we aim to better understand the intricate relationship between current management practices and their long-term effect on animal health. |
| first_indexed | 2024-04-24T20:26:41Z |
| format | Article |
| id | doaj.art-3561c8de4c01426eb8e0acdc6cb3f4b7 |
| institution | Directory Open Access Journal |
| issn | 0022-0302 |
| language | English |
| last_indexed | 2024-04-24T20:26:41Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Dairy Science |
| spelling | doaj.art-3561c8de4c01426eb8e0acdc6cb3f4b72024-03-22T05:38:21ZengElsevierJournal of Dairy Science0022-03022024-04-01107425432555Graduate Student Literature Review: Developmental adaptations of immune function in calves and the influence of the intestinal microbiota in health and diseaseL.R. Cangiano0C. Villot1L.L. Guan2I.R. Ipharraguerre3M.A. Steele4Department of Animal and Dairy Sciences, University of Wisconsin–Madison, Madison, WI 53706; Department of Animal Biosciences, Animal Science and Nutrition, University of Guelph, Guelph, ON, Canada N1G 1Y2; Corresponding authorLallemand Animal Nutrition, F-31702 Blagnac, France, and Milwaukee, WI 53218Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada, T6G 2P5Institute of Human Nutrition and Food Science, University of Kiel, D-24118 Kiel, GermanyDepartment of Animal Biosciences, Animal Science and Nutrition, University of Guelph, Guelph, ON, Canada N1G 1Y2ABSTRACT: This graduate student literature review provides an examination of the ontological adaptations of the calf's immune system and how the intestinal microbiota influences calf immune function in health and disease. Within dairy rearing systems, various nutritional and management factors have emerged as critical determinants of development influencing multiple physiological axes in the calf. Furthermore, we discuss how multiple pre- and postnatal maternal factors influence the trajectory of immune development in favor of establishing regulatory networks to successfully cope with the new environment, while providing early immune protection via immune passive transfer from colostrum. Additionally, our review provides insights into the current understanding of how the intestinal microbiota contributes to the development of the intestinal and systemic immune system in calves. Lastly, we address potential concerns related to the use of prophylactic antimicrobials and waste milk, specifically examining their adverse effects on intestinal health and metabolic function. By examining these factors, we aim to better understand the intricate relationship between current management practices and their long-term effect on animal health.http://www.sciencedirect.com/science/article/pii/S0022030223007877immune developmentmucosal immunitygut microbiomeantimicrobials |
| spellingShingle | L.R. Cangiano C. Villot L.L. Guan I.R. Ipharraguerre M.A. Steele Graduate Student Literature Review: Developmental adaptations of immune function in calves and the influence of the intestinal microbiota in health and disease Journal of Dairy Science immune development mucosal immunity gut microbiome antimicrobials |
| title | Graduate Student Literature Review: Developmental adaptations of immune function in calves and the influence of the intestinal microbiota in health and disease |
| title_full | Graduate Student Literature Review: Developmental adaptations of immune function in calves and the influence of the intestinal microbiota in health and disease |
| title_fullStr | Graduate Student Literature Review: Developmental adaptations of immune function in calves and the influence of the intestinal microbiota in health and disease |
| title_full_unstemmed | Graduate Student Literature Review: Developmental adaptations of immune function in calves and the influence of the intestinal microbiota in health and disease |
| title_short | Graduate Student Literature Review: Developmental adaptations of immune function in calves and the influence of the intestinal microbiota in health and disease |
| title_sort | graduate student literature review developmental adaptations of immune function in calves and the influence of the intestinal microbiota in health and disease |
| topic | immune development mucosal immunity gut microbiome antimicrobials |
| url | http://www.sciencedirect.com/science/article/pii/S0022030223007877 |
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