Electrospun Polycrown Ether Composite Nanofibers as an Adsorbent for On-Line Solid Phase Extraction of Eight Bisphenols from Drinking Water Samples with Column-Switching Prior to High Performance Liquid Chromatography
Bisphenols (BPs) are a class of endocrine disruptors widely existing in the environment. They have a great impact on human health owing to their environmental endocrine disrupting effects, chronic toxicity, neurotoxicity, cytotoxicity and genetic toxicity. In this paper, an on-line packed fiber soli...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-11-01
|
| Series: | Polymers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4360/14/21/4765 |
| _version_ | 1797466657760739328 |
|---|---|
| author | Tong Xu Rui Zhang Yueling Bi Jingjing Li Xiaohuan Li Liqin Chen Zhongze Fang |
| author_facet | Tong Xu Rui Zhang Yueling Bi Jingjing Li Xiaohuan Li Liqin Chen Zhongze Fang |
| author_sort | Tong Xu |
| collection | DOAJ |
| description | Bisphenols (BPs) are a class of endocrine disruptors widely existing in the environment. They have a great impact on human health owing to their environmental endocrine disrupting effects, chronic toxicity, neurotoxicity, cytotoxicity and genetic toxicity. In this paper, an on-line packed fiber solid phase extraction (PFSPE) coupling with column-switching HPLC-FLD determination method was developed for the determination of eight BPs in drinking water. The poly (dibenzo-18-crown-6-ether)/polystyrene composite nanofibers (PDB18C6/PS) were prepared by electrospinning and used as an adsorbent for the on-line PFSPE column. The on-line PFSPE-HPLC equipment contained a dual ternary pump and a switching valve to enable enrichment, purification, and analysis directly in the system. The results showed that the proposed on-line PFSPE-HPLC-FLD method realized the simultaneous separation and detection of eight BPs: BPF, BPE, BPA, BPB, BPAF, BPAP, BPC and BPZ. The curves of the target analytes were prepared with good correlation coefficient values (r<sup>2</sup> > 0.998) in the range of 50–1000 pg/mL. The limit of detection (S/N = 3) was 20 pg/mL, the limit of quantitation (S/N = 10) is 50 pg/mL. The recoveries of eight BPs were 94.8–127.3%, and the intra-day precisions (RSD) were less than 10%. The PFSPE column made of the PDB18C6/PS composite nanofibers has stable properties and can be reused at least 200 times. In the detection of drinking water samples, BPZ was detected in nearly 80% of drinking water samples, and BPA, BPAP, BPF and BPAF were also detected in some water samples. This high level of integration and automation was achieved in pretreatment of eight BPs from water samples. The proposed simple, rapid, and practical method has been successfully applied to the detection of eight BPs in drinking water, which can provide powerful technical support for drinking water quality and safety monitoring. |
| first_indexed | 2024-03-09T18:42:49Z |
| format | Article |
| id | doaj.art-3562b348fe3c4c048ddbf494d7bd9847 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-09T18:42:49Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-3562b348fe3c4c048ddbf494d7bd98472023-11-24T06:31:39ZengMDPI AGPolymers2073-43602022-11-011421476510.3390/polym14214765Electrospun Polycrown Ether Composite Nanofibers as an Adsorbent for On-Line Solid Phase Extraction of Eight Bisphenols from Drinking Water Samples with Column-Switching Prior to High Performance Liquid ChromatographyTong Xu0Rui Zhang1Yueling Bi2Jingjing Li3Xiaohuan Li4Liqin Chen5Zhongze Fang6Department of Toxicology and Sanitary Chemistry, School of Public Health, Tianjin Medical University, Tianjin 300070, ChinaDepartment of Toxicology and Sanitary Chemistry, School of Public Health, Tianjin Medical University, Tianjin 300070, ChinaDepartment of Pharmacy, Tianjin Xiqing Hospital, Tianjin 300380, ChinaDepartment of Toxicology and Sanitary Chemistry, School of Public Health, Tianjin Medical University, Tianjin 300070, ChinaDepartment of Toxicology and Sanitary Chemistry, School of Public Health, Tianjin Medical University, Tianjin 300070, ChinaDepartment of Toxicology and Sanitary Chemistry, School of Public Health, Tianjin Medical University, Tianjin 300070, ChinaDepartment of Toxicology and Sanitary Chemistry, School of Public Health, Tianjin Medical University, Tianjin 300070, ChinaBisphenols (BPs) are a class of endocrine disruptors widely existing in the environment. They have a great impact on human health owing to their environmental endocrine disrupting effects, chronic toxicity, neurotoxicity, cytotoxicity and genetic toxicity. In this paper, an on-line packed fiber solid phase extraction (PFSPE) coupling with column-switching HPLC-FLD determination method was developed for the determination of eight BPs in drinking water. The poly (dibenzo-18-crown-6-ether)/polystyrene composite nanofibers (PDB18C6/PS) were prepared by electrospinning and used as an adsorbent for the on-line PFSPE column. The on-line PFSPE-HPLC equipment contained a dual ternary pump and a switching valve to enable enrichment, purification, and analysis directly in the system. The results showed that the proposed on-line PFSPE-HPLC-FLD method realized the simultaneous separation and detection of eight BPs: BPF, BPE, BPA, BPB, BPAF, BPAP, BPC and BPZ. The curves of the target analytes were prepared with good correlation coefficient values (r<sup>2</sup> > 0.998) in the range of 50–1000 pg/mL. The limit of detection (S/N = 3) was 20 pg/mL, the limit of quantitation (S/N = 10) is 50 pg/mL. The recoveries of eight BPs were 94.8–127.3%, and the intra-day precisions (RSD) were less than 10%. The PFSPE column made of the PDB18C6/PS composite nanofibers has stable properties and can be reused at least 200 times. In the detection of drinking water samples, BPZ was detected in nearly 80% of drinking water samples, and BPA, BPAP, BPF and BPAF were also detected in some water samples. This high level of integration and automation was achieved in pretreatment of eight BPs from water samples. The proposed simple, rapid, and practical method has been successfully applied to the detection of eight BPs in drinking water, which can provide powerful technical support for drinking water quality and safety monitoring.https://www.mdpi.com/2073-4360/14/21/4765bisphenolspolymeric crown ether composite nanofiberon-line packed fiber solid phase extractionHPLC-FLD |
| spellingShingle | Tong Xu Rui Zhang Yueling Bi Jingjing Li Xiaohuan Li Liqin Chen Zhongze Fang Electrospun Polycrown Ether Composite Nanofibers as an Adsorbent for On-Line Solid Phase Extraction of Eight Bisphenols from Drinking Water Samples with Column-Switching Prior to High Performance Liquid Chromatography Polymers bisphenols polymeric crown ether composite nanofiber on-line packed fiber solid phase extraction HPLC-FLD |
| title | Electrospun Polycrown Ether Composite Nanofibers as an Adsorbent for On-Line Solid Phase Extraction of Eight Bisphenols from Drinking Water Samples with Column-Switching Prior to High Performance Liquid Chromatography |
| title_full | Electrospun Polycrown Ether Composite Nanofibers as an Adsorbent for On-Line Solid Phase Extraction of Eight Bisphenols from Drinking Water Samples with Column-Switching Prior to High Performance Liquid Chromatography |
| title_fullStr | Electrospun Polycrown Ether Composite Nanofibers as an Adsorbent for On-Line Solid Phase Extraction of Eight Bisphenols from Drinking Water Samples with Column-Switching Prior to High Performance Liquid Chromatography |
| title_full_unstemmed | Electrospun Polycrown Ether Composite Nanofibers as an Adsorbent for On-Line Solid Phase Extraction of Eight Bisphenols from Drinking Water Samples with Column-Switching Prior to High Performance Liquid Chromatography |
| title_short | Electrospun Polycrown Ether Composite Nanofibers as an Adsorbent for On-Line Solid Phase Extraction of Eight Bisphenols from Drinking Water Samples with Column-Switching Prior to High Performance Liquid Chromatography |
| title_sort | electrospun polycrown ether composite nanofibers as an adsorbent for on line solid phase extraction of eight bisphenols from drinking water samples with column switching prior to high performance liquid chromatography |
| topic | bisphenols polymeric crown ether composite nanofiber on-line packed fiber solid phase extraction HPLC-FLD |
| url | https://www.mdpi.com/2073-4360/14/21/4765 |
| work_keys_str_mv | AT tongxu electrospunpolycrownethercompositenanofibersasanadsorbentforonlinesolidphaseextractionofeightbisphenolsfromdrinkingwatersampleswithcolumnswitchingpriortohighperformanceliquidchromatography AT ruizhang electrospunpolycrownethercompositenanofibersasanadsorbentforonlinesolidphaseextractionofeightbisphenolsfromdrinkingwatersampleswithcolumnswitchingpriortohighperformanceliquidchromatography AT yuelingbi electrospunpolycrownethercompositenanofibersasanadsorbentforonlinesolidphaseextractionofeightbisphenolsfromdrinkingwatersampleswithcolumnswitchingpriortohighperformanceliquidchromatography AT jingjingli electrospunpolycrownethercompositenanofibersasanadsorbentforonlinesolidphaseextractionofeightbisphenolsfromdrinkingwatersampleswithcolumnswitchingpriortohighperformanceliquidchromatography AT xiaohuanli electrospunpolycrownethercompositenanofibersasanadsorbentforonlinesolidphaseextractionofeightbisphenolsfromdrinkingwatersampleswithcolumnswitchingpriortohighperformanceliquidchromatography AT liqinchen electrospunpolycrownethercompositenanofibersasanadsorbentforonlinesolidphaseextractionofeightbisphenolsfromdrinkingwatersampleswithcolumnswitchingpriortohighperformanceliquidchromatography AT zhongzefang electrospunpolycrownethercompositenanofibersasanadsorbentforonlinesolidphaseextractionofeightbisphenolsfromdrinkingwatersampleswithcolumnswitchingpriortohighperformanceliquidchromatography |