Effect of Personalized Nutrition on Dietary, Physical Activity, and Health Outcomes: A Systematic Review of Randomized Trials
Personalized nutrition is an approach that tailors nutrition advice to individuals based on an individual’s genetic information. Despite interest among scholars, the impact of this approach on lifestyle habits and health has not been adequately explored. Hence, a systematic review of randomized tria...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/14/19/4104 |
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| author | Sangeetha Shyam Ke Xin Lee Angeline Shu Wei Tan Tien An Khoo Shivani Harikrishnan Shehzeen Alnoor Lalani Amutha Ramadas |
| author_facet | Sangeetha Shyam Ke Xin Lee Angeline Shu Wei Tan Tien An Khoo Shivani Harikrishnan Shehzeen Alnoor Lalani Amutha Ramadas |
| author_sort | Sangeetha Shyam |
| collection | DOAJ |
| description | Personalized nutrition is an approach that tailors nutrition advice to individuals based on an individual’s genetic information. Despite interest among scholars, the impact of this approach on lifestyle habits and health has not been adequately explored. Hence, a systematic review of randomized trials reporting on the effects of personalized nutrition on dietary, physical activity, and health outcomes was conducted. A systematic search of seven electronic databases and a manual search resulted in identifying nine relevant trials. Cochrane’s Risk of Bias was used to determine the trials’ methodological quality. Although the trials were of moderate to high quality, the findings did not show consistent benefits of personalized nutrition in improving dietary, behavioral, or health outcomes. There was also a lack of evidence from regions other than North America and Europe or among individuals with diseases, affecting the generalizability of the results. Furthermore, the complex relationship between genes, interventions, and outcomes may also have contributed to the scarcity of positive findings. We have suggested several areas for improvement for future trials regarding personalized nutrition. |
| first_indexed | 2024-03-09T21:18:40Z |
| format | Article |
| id | doaj.art-3563509413c54544819d004e04ae4d91 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T21:18:40Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-3563509413c54544819d004e04ae4d912023-11-23T21:25:41ZengMDPI AGNutrients2072-66432022-10-011419410410.3390/nu14194104Effect of Personalized Nutrition on Dietary, Physical Activity, and Health Outcomes: A Systematic Review of Randomized TrialsSangeetha Shyam0Ke Xin Lee1Angeline Shu Wei Tan2Tien An Khoo3Shivani Harikrishnan4Shehzeen Alnoor Lalani5Amutha Ramadas6Centre for Translational Research, IMU Institute for Research and Development (IRDI), International Medical University (IMU), Jalan Jalil Perkasa 19, Bukit Jalil, Kuala Lumpur 57000, MalaysiaJeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, MalaysiaJeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, MalaysiaJeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, MalaysiaWarwick Medical School, University of Warwick, Coventry CV4 7HL, UKDalhousie Medicine DMNS, Dalhousie University, 5849 University Avenue, Halifax, NS B3H 4R2, CanadaJeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, MalaysiaPersonalized nutrition is an approach that tailors nutrition advice to individuals based on an individual’s genetic information. Despite interest among scholars, the impact of this approach on lifestyle habits and health has not been adequately explored. Hence, a systematic review of randomized trials reporting on the effects of personalized nutrition on dietary, physical activity, and health outcomes was conducted. A systematic search of seven electronic databases and a manual search resulted in identifying nine relevant trials. Cochrane’s Risk of Bias was used to determine the trials’ methodological quality. Although the trials were of moderate to high quality, the findings did not show consistent benefits of personalized nutrition in improving dietary, behavioral, or health outcomes. There was also a lack of evidence from regions other than North America and Europe or among individuals with diseases, affecting the generalizability of the results. Furthermore, the complex relationship between genes, interventions, and outcomes may also have contributed to the scarcity of positive findings. We have suggested several areas for improvement for future trials regarding personalized nutrition.https://www.mdpi.com/2072-6643/14/19/4104personalized nutritionnutrigeneticsnutrigenomicsnutrition intervention |
| spellingShingle | Sangeetha Shyam Ke Xin Lee Angeline Shu Wei Tan Tien An Khoo Shivani Harikrishnan Shehzeen Alnoor Lalani Amutha Ramadas Effect of Personalized Nutrition on Dietary, Physical Activity, and Health Outcomes: A Systematic Review of Randomized Trials Nutrients personalized nutrition nutrigenetics nutrigenomics nutrition intervention |
| title | Effect of Personalized Nutrition on Dietary, Physical Activity, and Health Outcomes: A Systematic Review of Randomized Trials |
| title_full | Effect of Personalized Nutrition on Dietary, Physical Activity, and Health Outcomes: A Systematic Review of Randomized Trials |
| title_fullStr | Effect of Personalized Nutrition on Dietary, Physical Activity, and Health Outcomes: A Systematic Review of Randomized Trials |
| title_full_unstemmed | Effect of Personalized Nutrition on Dietary, Physical Activity, and Health Outcomes: A Systematic Review of Randomized Trials |
| title_short | Effect of Personalized Nutrition on Dietary, Physical Activity, and Health Outcomes: A Systematic Review of Randomized Trials |
| title_sort | effect of personalized nutrition on dietary physical activity and health outcomes a systematic review of randomized trials |
| topic | personalized nutrition nutrigenetics nutrigenomics nutrition intervention |
| url | https://www.mdpi.com/2072-6643/14/19/4104 |
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