Establishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs.

Establishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs.

Sphingolipids are essential components in eukaryotes and have various cellular functions. Recent developments in genome-editing technologies have facilitated gene disruption in various organisms and cell lines. We here show the disruption of various sphingolipid metabolic genes in human cervical car...

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Bibliographic Details
Main Authors:	Toshiyuki Yamaji, Kentaro Hanada
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3912166?pdf=render

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