miR-10b suppresses cell invasion and metastasis through targeting HOXA3 regulated by FAK/YAP signaling pathway in clear-cell renal cell carcinoma

miR-10b suppresses cell invasion and metastasis through targeting HOXA3 regulated by FAK/YAP signaling pathway in clear-cell renal cell carcinoma

Abstract Background MicroRNAs have been related to tumor progression in diverse human cancers including clear-cell renal cell carcinoma (ccRCC). Previous study has suggested the important regulation function of miR-10b in ccRCC. However, the direct target of miR-10b in ccRCC and the related molecula...

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Bibliographic Details
Main Authors: Cheng He, Zhi-Yong Chen, Yang Li, Zhong-Qing Yang, Feng Zeng, Yu Cui, Yao He, Jin-Bo Chen, He-Qun Chen
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Nephrology
Subjects:
miR-10b
ccRCC
Metastasis
HOXA3
FAK/YAP
Online Access:http://link.springer.com/article/10.1186/s12882-019-1322-1

Internet

http://link.springer.com/article/10.1186/s12882-019-1322-1

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