First report of OXA-48-producing Klebsiella pneumoniae strains in Iran
[english] Carbapenem-resistant are increasingly reported worldwide and cause therapeutic problem in health care facilities. In this study 28 imipenem-resistant were examined for expression of carbapenemases by phenotypic and genotypic methods. Modified Hodge Test (MHT), CarbaNP test were used for...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | deu |
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German Medical Science GMS Publishing House
2014-03-01
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| Series: | GMS Hygiene and Infection Control |
| Subjects: | |
| Online Access: | http://www.egms.de/static/en/journals/dgkh/2014-9/dgkh000227.shtml |
| _version_ | 1828258041854689280 |
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| author | Azimi, Leila Nordmann, Patrice Lari, Abdolaziz Rastegar Bonnin, Rémy A. |
| author_facet | Azimi, Leila Nordmann, Patrice Lari, Abdolaziz Rastegar Bonnin, Rémy A. |
| author_sort | Azimi, Leila |
| collection | DOAJ |
| description | [english] Carbapenem-resistant are increasingly reported worldwide and cause therapeutic problem in health care facilities. In this study 28 imipenem-resistant were examined for expression of carbapenemases by phenotypic and genotypic methods. Modified Hodge Test (MHT), CarbaNP test were used for phenotypic detection, and PCR using specific primers for the detection of and type carbapenemases with specific primers were performed. MHT and CarbaNP tests were positive for all of imipenem-resistant . The gene was detected in 27/28 isolates. One isolate was positive for the presence of the gene. According to our results NP test and MHT have high sensitivity and specificity for detection of those carbapenemases. This study reports the first cases of OXA-48-producing in Iran. |
| first_indexed | 2024-04-13T02:49:20Z |
| format | Article |
| id | doaj.art-3567f152792f4ef4b550d13488c8c59d |
| institution | Directory Open Access Journal |
| issn | 2196-5226 |
| language | deu |
| last_indexed | 2024-04-13T02:49:20Z |
| publishDate | 2014-03-01 |
| publisher | German Medical Science GMS Publishing House |
| record_format | Article |
| series | GMS Hygiene and Infection Control |
| spelling | doaj.art-3567f152792f4ef4b550d13488c8c59d2022-12-22T03:05:54ZdeuGerman Medical Science GMS Publishing HouseGMS Hygiene and Infection Control2196-52262014-03-0191Doc0710.3205/dgkh000227First report of OXA-48-producing Klebsiella pneumoniae strains in IranAzimi, Leila0Nordmann, Patrice1Lari, Abdolaziz Rastegar2Bonnin, Rémy A.3Antimicrobial Resistance Research Center, Iran University of Medical Sciences, Tehran, IranINSERM U914, Le Kremlin-Bicêtre, FranceAntimicrobial Resistance Research Center, Iran University of Medical Sciences, Tehran, IranINSERM U914, Le Kremlin-Bicêtre, France[english] Carbapenem-resistant are increasingly reported worldwide and cause therapeutic problem in health care facilities. In this study 28 imipenem-resistant were examined for expression of carbapenemases by phenotypic and genotypic methods. Modified Hodge Test (MHT), CarbaNP test were used for phenotypic detection, and PCR using specific primers for the detection of and type carbapenemases with specific primers were performed. MHT and CarbaNP tests were positive for all of imipenem-resistant . The gene was detected in 27/28 isolates. One isolate was positive for the presence of the gene. According to our results NP test and MHT have high sensitivity and specificity for detection of those carbapenemases. This study reports the first cases of OXA-48-producing in Iran.http://www.egms.de/static/en/journals/dgkh/2014-9/dgkh000227.shtmlcarbapenemKlebsiella pneumoniaeCarbaNP testMHTOXA-48 |
| spellingShingle | Azimi, Leila Nordmann, Patrice Lari, Abdolaziz Rastegar Bonnin, Rémy A. First report of OXA-48-producing Klebsiella pneumoniae strains in Iran GMS Hygiene and Infection Control carbapenem Klebsiella pneumoniae CarbaNP test MHT OXA-48 |
| title | First report of OXA-48-producing Klebsiella pneumoniae strains in Iran |
| title_full | First report of OXA-48-producing Klebsiella pneumoniae strains in Iran |
| title_fullStr | First report of OXA-48-producing Klebsiella pneumoniae strains in Iran |
| title_full_unstemmed | First report of OXA-48-producing Klebsiella pneumoniae strains in Iran |
| title_short | First report of OXA-48-producing Klebsiella pneumoniae strains in Iran |
| title_sort | first report of oxa 48 producing klebsiella pneumoniae strains in iran |
| topic | carbapenem Klebsiella pneumoniae CarbaNP test MHT OXA-48 |
| url | http://www.egms.de/static/en/journals/dgkh/2014-9/dgkh000227.shtml |
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