Sequential treatment with zoledronic acid followed by teriparatide or vice versa increases bone mineral density and bone strength in ovariectomized rats

Bisphosphonates (BPs) and teriparatide (TPTD) are both effective treatments for osteoporosis, but BP treatment prior to daily TPTD treatment has been shown to impair the effect of TPTD in some clinical studies. In contrast, the loss of bone mineral density (BMD) that occurs after withdrawal of TPTD...

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Bibliographic Details
Main Authors: T. Shimizu, T. Tanaka, T. Kobayashi, I. Kudo, M. Nakatsugawa, A. Takakura, R. Takao-Kawabata, T. Ishizuya
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Bone Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187217300177