State of the Art in Carbon Nanomaterials for Photoacoustic Imaging
Photoacoustic imaging using energy conversion from light to ultrasound waves has been developed as a powerful tool to investigate in vivo phenomena due to their complex characteristics. In photoacoustic imaging, endogenous chromophores such as oxygenated hemoglobin, deoxygenated hemoglobin, melanin,...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/10/6/1374 |
| _version_ | 1797489651650396160 |
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| author | Moon Sung Kang Haeni Lee Seung Jo Jeong Tae Joong Eom Jeesu Kim Dong-Wook Han |
| author_facet | Moon Sung Kang Haeni Lee Seung Jo Jeong Tae Joong Eom Jeesu Kim Dong-Wook Han |
| author_sort | Moon Sung Kang |
| collection | DOAJ |
| description | Photoacoustic imaging using energy conversion from light to ultrasound waves has been developed as a powerful tool to investigate in vivo phenomena due to their complex characteristics. In photoacoustic imaging, endogenous chromophores such as oxygenated hemoglobin, deoxygenated hemoglobin, melanin, and lipid provide useful biomedical information at the molecular level. However, these intrinsic absorbers show strong absorbance only in visible or infrared optical windows and have limited light transmission, making them difficult to apply for clinical translation. Therefore, the development of novel exogenous contrast agents capable of increasing imaging depth while ensuring strong light absorption is required. We report here the application of carbon nanomaterials that exhibit unique physical, mechanical, and electrochemical properties as imaging probes in photoacoustic imaging. Classified into specific structures, carbon nanomaterials are synthesized with different substances according to the imaging purposes to modulate the absorption spectra and highly enhance photoacoustic signals. In addition, functional drugs can be loaded into the carbon nanomaterials composite, and effective in vivo monitoring and photothermal therapy can be performed with cell-specific targeting. Diverse applied cases suggest the high potential of carbon nanomaterial-based photoacoustic imaging in in vivo monitoring for clinical research. |
| first_indexed | 2024-03-10T00:20:39Z |
| format | Article |
| id | doaj.art-356d8612bac1456e9dbffb6a58b4ef61 |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-10T00:20:39Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-356d8612bac1456e9dbffb6a58b4ef612023-11-23T15:43:44ZengMDPI AGBiomedicines2227-90592022-06-01106137410.3390/biomedicines10061374State of the Art in Carbon Nanomaterials for Photoacoustic ImagingMoon Sung Kang0Haeni Lee1Seung Jo Jeong2Tae Joong Eom3Jeesu Kim4Dong-Wook Han5Department of Cogno-Mechatronics Engineering, College of Nanoscience & Nanotechnology, Pusan National University, Busan 46241, KoreaDepartment of Cogno-Mechatronics Engineering, College of Nanoscience & Nanotechnology, Pusan National University, Busan 46241, KoreaBio-IT Fusion Technology Research Institute, Pusan National University, Busan 46241, KoreaDepartment of Cogno-Mechatronics Engineering, College of Nanoscience & Nanotechnology, Pusan National University, Busan 46241, KoreaDepartment of Cogno-Mechatronics Engineering, College of Nanoscience & Nanotechnology, Pusan National University, Busan 46241, KoreaDepartment of Cogno-Mechatronics Engineering, College of Nanoscience & Nanotechnology, Pusan National University, Busan 46241, KoreaPhotoacoustic imaging using energy conversion from light to ultrasound waves has been developed as a powerful tool to investigate in vivo phenomena due to their complex characteristics. In photoacoustic imaging, endogenous chromophores such as oxygenated hemoglobin, deoxygenated hemoglobin, melanin, and lipid provide useful biomedical information at the molecular level. However, these intrinsic absorbers show strong absorbance only in visible or infrared optical windows and have limited light transmission, making them difficult to apply for clinical translation. Therefore, the development of novel exogenous contrast agents capable of increasing imaging depth while ensuring strong light absorption is required. We report here the application of carbon nanomaterials that exhibit unique physical, mechanical, and electrochemical properties as imaging probes in photoacoustic imaging. Classified into specific structures, carbon nanomaterials are synthesized with different substances according to the imaging purposes to modulate the absorption spectra and highly enhance photoacoustic signals. In addition, functional drugs can be loaded into the carbon nanomaterials composite, and effective in vivo monitoring and photothermal therapy can be performed with cell-specific targeting. Diverse applied cases suggest the high potential of carbon nanomaterial-based photoacoustic imaging in in vivo monitoring for clinical research.https://www.mdpi.com/2227-9059/10/6/1374carbon nanomaterialsphototherapyphotoacoustic imagingimage-guided therapy |
| spellingShingle | Moon Sung Kang Haeni Lee Seung Jo Jeong Tae Joong Eom Jeesu Kim Dong-Wook Han State of the Art in Carbon Nanomaterials for Photoacoustic Imaging Biomedicines carbon nanomaterials phototherapy photoacoustic imaging image-guided therapy |
| title | State of the Art in Carbon Nanomaterials for Photoacoustic Imaging |
| title_full | State of the Art in Carbon Nanomaterials for Photoacoustic Imaging |
| title_fullStr | State of the Art in Carbon Nanomaterials for Photoacoustic Imaging |
| title_full_unstemmed | State of the Art in Carbon Nanomaterials for Photoacoustic Imaging |
| title_short | State of the Art in Carbon Nanomaterials for Photoacoustic Imaging |
| title_sort | state of the art in carbon nanomaterials for photoacoustic imaging |
| topic | carbon nanomaterials phototherapy photoacoustic imaging image-guided therapy |
| url | https://www.mdpi.com/2227-9059/10/6/1374 |
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