Giant Cell Arteritis Presenting with Mania, Psychosis, and Cognitive Dysfunction: A Case Report

Background. Giant cell arteritis (GCA) is an autoimmune vasculitis affecting medium- and large-sized arteries. Vascular inflammation may lead to narrowing of the arterial lumen, and acute occlusion may result in vision loss and stroke. The classical symptoms include headache, fever, and jaw claudica...

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Main Authors: Heidi Madeleine Latvala, Solveig Klæbo Reitan, Arne Einar Vaaler
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2023/7989712
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author Heidi Madeleine Latvala
Solveig Klæbo Reitan
Arne Einar Vaaler
author_facet Heidi Madeleine Latvala
Solveig Klæbo Reitan
Arne Einar Vaaler
author_sort Heidi Madeleine Latvala
collection DOAJ
description Background. Giant cell arteritis (GCA) is an autoimmune vasculitis affecting medium- and large-sized arteries. Vascular inflammation may lead to narrowing of the arterial lumen, and acute occlusion may result in vision loss and stroke. The classical symptoms include headache, fever, and jaw claudication. However, there is an increasing recognition of atypical presentations. Case Presentation. We report a case of a 70-year-old woman presenting with fluctuating manic symptoms and confusion, in addition to headache and musculoskeletal pain. After diagnosis of GCA, treatment with corticosteroids gradually improved the somatic symptoms. Conclusion. Corticosteroids led to a temporary exacerbation of manic symptoms, which improved after 3 to 4 weeks of continuous treatment, indicating that the symptoms were most likely associated with GCA. The patient manifested with clinical features and a clinical course that has, to our knowledge, not been described or published before. Therefore, GCA may be an underdiagnosed disease in psychiatric populations and should be considered in case of atypical, new-onset psychiatric disorders in the elderly.
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spelling doaj.art-356dfdabf491477da136d06b98e7e6ad2023-02-20T01:57:42ZengHindawi LimitedCase Reports in Psychiatry2090-68382023-01-01202310.1155/2023/7989712Giant Cell Arteritis Presenting with Mania, Psychosis, and Cognitive Dysfunction: A Case ReportHeidi Madeleine Latvala0Solveig Klæbo Reitan1Arne Einar Vaaler2Department of AddictionDepartment of Mental HealthDepartment of Mental HealthBackground. Giant cell arteritis (GCA) is an autoimmune vasculitis affecting medium- and large-sized arteries. Vascular inflammation may lead to narrowing of the arterial lumen, and acute occlusion may result in vision loss and stroke. The classical symptoms include headache, fever, and jaw claudication. However, there is an increasing recognition of atypical presentations. Case Presentation. We report a case of a 70-year-old woman presenting with fluctuating manic symptoms and confusion, in addition to headache and musculoskeletal pain. After diagnosis of GCA, treatment with corticosteroids gradually improved the somatic symptoms. Conclusion. Corticosteroids led to a temporary exacerbation of manic symptoms, which improved after 3 to 4 weeks of continuous treatment, indicating that the symptoms were most likely associated with GCA. The patient manifested with clinical features and a clinical course that has, to our knowledge, not been described or published before. Therefore, GCA may be an underdiagnosed disease in psychiatric populations and should be considered in case of atypical, new-onset psychiatric disorders in the elderly.http://dx.doi.org/10.1155/2023/7989712
spellingShingle Heidi Madeleine Latvala
Solveig Klæbo Reitan
Arne Einar Vaaler
Giant Cell Arteritis Presenting with Mania, Psychosis, and Cognitive Dysfunction: A Case Report
Case Reports in Psychiatry
title Giant Cell Arteritis Presenting with Mania, Psychosis, and Cognitive Dysfunction: A Case Report
title_full Giant Cell Arteritis Presenting with Mania, Psychosis, and Cognitive Dysfunction: A Case Report
title_fullStr Giant Cell Arteritis Presenting with Mania, Psychosis, and Cognitive Dysfunction: A Case Report
title_full_unstemmed Giant Cell Arteritis Presenting with Mania, Psychosis, and Cognitive Dysfunction: A Case Report
title_short Giant Cell Arteritis Presenting with Mania, Psychosis, and Cognitive Dysfunction: A Case Report
title_sort giant cell arteritis presenting with mania psychosis and cognitive dysfunction a case report
url http://dx.doi.org/10.1155/2023/7989712
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