Transient Delivery of A-C/EBP Protein Perturbs Differentiation of 3T3-L1 Cells and Induces Preadipocyte Marker Genes

Transient Delivery of A-C/EBP Protein Perturbs Differentiation of 3T3-L1 Cells and Induces Preadipocyte Marker Genes

Transformation of committed 3T3-L1 preadipocytes to lipid-laden adipocytes involves the timely appearance of numerous transcription factors (TFs); foremost among them, C/EBPβ is expressed during the early phases of differentiation. Here, we describe liposome-mediated protein transfection approach to...

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Bibliographic Details
Main Authors: Nishtha Sharma, Raminder Kaur, Binduma Yadav, Koushik Shah, Harshita Pandey, Diksha Choudhary, Prateek Jain, Aanchal Aggarwal, Charles Vinson, Vikas Rishi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
C/EBPβ
protein transfection
adipogenesis
3T3-L1
dedifferentiation
obesity
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2020.603168/full

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