TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®»
Toxicological research of combined antitubercular preparation. «Protub-2®» that contains a pyridoxine hydrochloride (vitamin B). It was established, that introduction of pyridoxine hydrochloride in the structure of preparation «Protub-2®» allowed to reduce the majority of toxic effects caused by iso...
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Format: | Article |
Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2012-07-01
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Series: | Acta Biomedica Scientifica |
Subjects: | |
Online Access: | https://www.actabiomedica.ru/jour/article/view/1061 |
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author | K. I. Usov G. G. Yushkov Yu. Yu. Schaura A. S. Guschin |
author_facet | K. I. Usov G. G. Yushkov Yu. Yu. Schaura A. S. Guschin |
author_sort | K. I. Usov |
collection | DOAJ |
description | Toxicological research of combined antitubercular preparation. «Protub-2®» that contains a pyridoxine hydrochloride (vitamin B). It was established, that introduction of pyridoxine hydrochloride in the structure of preparation «Protub-2®» allowed to reduce the majority of toxic effects caused by isoniazid and rifampicin that are parts of studied, preparation. |
first_indexed | 2024-03-08T12:21:39Z |
format | Article |
id | doaj.art-356fdb07e2564dc990fdeb6099af58e1 |
institution | Directory Open Access Journal |
issn | 2541-9420 2587-9596 |
language | Russian |
last_indexed | 2024-04-24T17:22:22Z |
publishDate | 2012-07-01 |
publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
record_format | Article |
series | Acta Biomedica Scientifica |
spelling | doaj.art-356fdb07e2564dc990fdeb6099af58e12024-03-28T07:49:07ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962012-07-0104(2)2012051007TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®»K. I. Usov0G. G. Yushkov1Yu. Yu. Schaura2A. S. Guschin3Angarsk State Technical AcademyAngarsk State Technical AcademyAngarsk State Technical AcademyPublic Corporation «Farmasintez», IrkutskToxicological research of combined antitubercular preparation. «Protub-2®» that contains a pyridoxine hydrochloride (vitamin B). It was established, that introduction of pyridoxine hydrochloride in the structure of preparation «Protub-2®» allowed to reduce the majority of toxic effects caused by isoniazid and rifampicin that are parts of studied, preparation.https://www.actabiomedica.ru/jour/article/view/1061antitubercular preparationisoniazidrifampicinpyridoxine hydrochloride (vitamin b<sub>6</sub>)toxicityxanthurenic acid |
spellingShingle | K. I. Usov G. G. Yushkov Yu. Yu. Schaura A. S. Guschin TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®» Acta Biomedica Scientifica antitubercular preparation isoniazid rifampicin pyridoxine hydrochloride (vitamin b<sub>6</sub>) toxicity xanthurenic acid |
title | TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®» |
title_full | TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®» |
title_fullStr | TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®» |
title_full_unstemmed | TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®» |
title_short | TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®» |
title_sort | toxicological estimation of combined antitubercular preparation protub 2 r |
topic | antitubercular preparation isoniazid rifampicin pyridoxine hydrochloride (vitamin b<sub>6</sub>) toxicity xanthurenic acid |
url | https://www.actabiomedica.ru/jour/article/view/1061 |
work_keys_str_mv | AT kiusov toxicologicalestimationofcombinedantitubercularpreparationprotub2 AT ggyushkov toxicologicalestimationofcombinedantitubercularpreparationprotub2 AT yuyuschaura toxicologicalestimationofcombinedantitubercularpreparationprotub2 AT asguschin toxicologicalestimationofcombinedantitubercularpreparationprotub2 |