TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®»

Toxicological research of combined antitubercular preparation. «Protub-2®» that contains a pyridoxine hydrochloride (vitamin B). It was established, that introduction of pyridoxine hydrochloride in the structure of preparation «Protub-2®» allowed to reduce the majority of toxic effects caused by iso...

Full description

Bibliographic Details
Main Authors: K. I. Usov, G. G. Yushkov, Yu. Yu. Schaura, A. S. Guschin
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2012-07-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/1061
_version_ 1797237603348512768
author K. I. Usov
G. G. Yushkov
Yu. Yu. Schaura
A. S. Guschin
author_facet K. I. Usov
G. G. Yushkov
Yu. Yu. Schaura
A. S. Guschin
author_sort K. I. Usov
collection DOAJ
description Toxicological research of combined antitubercular preparation. «Protub-2®» that contains a pyridoxine hydrochloride (vitamin B). It was established, that introduction of pyridoxine hydrochloride in the structure of preparation «Protub-2®» allowed to reduce the majority of toxic effects caused by isoniazid and rifampicin that are parts of studied, preparation.
first_indexed 2024-03-08T12:21:39Z
format Article
id doaj.art-356fdb07e2564dc990fdeb6099af58e1
institution Directory Open Access Journal
issn 2541-9420
2587-9596
language Russian
last_indexed 2024-04-24T17:22:22Z
publishDate 2012-07-01
publisher Scientific Сentre for Family Health and Human Reproduction Problems
record_format Article
series Acta Biomedica Scientifica
spelling doaj.art-356fdb07e2564dc990fdeb6099af58e12024-03-28T07:49:07ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962012-07-0104(2)2012051007TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®»K. I. Usov0G. G. Yushkov1Yu. Yu. Schaura2A. S. Guschin3Angarsk State Technical AcademyAngarsk State Technical AcademyAngarsk State Technical AcademyPublic Corporation «Farmasintez», IrkutskToxicological research of combined antitubercular preparation. «Protub-2®» that contains a pyridoxine hydrochloride (vitamin B). It was established, that introduction of pyridoxine hydrochloride in the structure of preparation «Protub-2®» allowed to reduce the majority of toxic effects caused by isoniazid and rifampicin that are parts of studied, preparation.https://www.actabiomedica.ru/jour/article/view/1061antitubercular preparationisoniazidrifampicinpyridoxine hydrochloride (vitamin b<sub>6</sub>)toxicityxanthurenic acid
spellingShingle K. I. Usov
G. G. Yushkov
Yu. Yu. Schaura
A. S. Guschin
TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®»
Acta Biomedica Scientifica
antitubercular preparation
isoniazid
rifampicin
pyridoxine hydrochloride (vitamin b<sub>6</sub>)
toxicity
xanthurenic acid
title TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®»
title_full TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®»
title_fullStr TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®»
title_full_unstemmed TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®»
title_short TOXICOLOGICAL ESTIMATION OF COMBINED ANTITUBERCULAR PREPARATION «PROTUB-2®»
title_sort toxicological estimation of combined antitubercular preparation protub 2 r
topic antitubercular preparation
isoniazid
rifampicin
pyridoxine hydrochloride (vitamin b<sub>6</sub>)
toxicity
xanthurenic acid
url https://www.actabiomedica.ru/jour/article/view/1061
work_keys_str_mv AT kiusov toxicologicalestimationofcombinedantitubercularpreparationprotub2
AT ggyushkov toxicologicalestimationofcombinedantitubercularpreparationprotub2
AT yuyuschaura toxicologicalestimationofcombinedantitubercularpreparationprotub2
AT asguschin toxicologicalestimationofcombinedantitubercularpreparationprotub2