Downregulation of MAPK/MAK/MRK overlapping kinase 1 in peripheral blood mononuclear cells of pediatric patients with type 1 diabetes mellitus

Downregulation of MAPK/MAK/MRK overlapping kinase 1 in peripheral blood mononuclear cells of pediatric patients with type 1 diabetes mellitus

Background: Type 1 diabetes mellitus (T1DM) is one of the most common endocrine diseases in children. T-cell autoreactivity toward b-cells is controlled by significant changes in metabolism of T cells. Mammalian target of rapamycin (mTOR) is an important intracellular regulator of metabolism and cel...

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Bibliographic Details
Main Authors: Sopić Miron, Ninić Ana, Ostanek Barbara, Bojanin Dragana, Milenković Tatjana, Munjas Jelena, Mihajlović Marija, Vekić Jelena, Marc Janja, Spasojević-Kalimanovska Vesna
Format: Article
Language:English
Published: Society of Medical Biochemists of Serbia, Belgrade 2022-01-01
Series:Journal of Medical Biochemistry
Subjects:
type 1 diabetes mellitus
mammalian target of rapamycin
mapk/mak/mrk overlapping kinase 1
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2022/1452-82582203282S.pdf

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