Pediatric vision screening using the plusoptiX A12C photoscreener in Chinese preschool children aged 3 to 4 years

Abstract This study evaluated the performance of plusoptiX A12C in detecting amblyopia risk factors (ARFs) in Chinese children aged 3-to-4-year. PlusoptiX examination was successfully conducted among 1,766 subjects without cycloplegia to detect refractive error, asymmetry and media opacity. Cyclople...

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Main Authors: Dan Huang, Xuejuan Chen, Xiaohan Zhang, Yue Wang, Hui Zhu, Hui Ding, Jing Bai, Ji Chen, Zhujun Fu, Zijin Wang, Hu Liu
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02246-6
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author Dan Huang
Xuejuan Chen
Xiaohan Zhang
Yue Wang
Hui Zhu
Hui Ding
Jing Bai
Ji Chen
Zhujun Fu
Zijin Wang
Hu Liu
author_facet Dan Huang
Xuejuan Chen
Xiaohan Zhang
Yue Wang
Hui Zhu
Hui Ding
Jing Bai
Ji Chen
Zhujun Fu
Zijin Wang
Hu Liu
author_sort Dan Huang
collection DOAJ
description Abstract This study evaluated the performance of plusoptiX A12C in detecting amblyopia risk factors (ARFs) in Chinese children aged 3-to-4-year. PlusoptiX examination was successfully conducted among 1,766 subjects without cycloplegia to detect refractive error, asymmetry and media opacity. Cycloplegic retinoscopy (CR) was conducted on 357 children suspected of having vision abnormalities. Statistical differences between CR and the device were confirmed using the mean spherical value (+1.41 ± 0.87 D versus +1.14 ± 0.81 D), cylindrical value (−0.47 ± 0.64 versus −0.84 ± 0.78) and spherical equivalent (SE) value (+1.17 ± 0.84 D versus +0.72 ± 0.64 D) (all P < 0.0001). In the emmetropia group, the differences were statistically significant for the cylinder and SE (all P < 0.0001) but not the sphere (P = 0.33). In the hyperopia group, the differences were statistically significant for the sphere, cylinder and SE (all P < 0.0001). For refractive and strabismic ARFs detection, the sensitivity, specificity, positive predictive value, and negative predictive value were calculated, respectively.
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spelling doaj.art-3571472034834df29bc491b7533aa77a2022-12-21T19:26:36ZengNature PortfolioScientific Reports2045-23222017-05-01711710.1038/s41598-017-02246-6Pediatric vision screening using the plusoptiX A12C photoscreener in Chinese preschool children aged 3 to 4 yearsDan Huang0Xuejuan Chen1Xiaohan Zhang2Yue Wang3Hui Zhu4Hui Ding5Jing Bai6Ji Chen7Zhujun Fu8Zijin Wang9Hu Liu10Department of Ophthalmology, The First Affiliated Hospital with Nanjing Medical UniversityDepartment of Ophthalmology, The First Affiliated Hospital with Nanjing Medical UniversityDepartment of Ophthalmology, The First Affiliated Hospital with Nanjing Medical UniversityDepartment of Ophthalmology, The First Affiliated Hospital with Nanjing Medical UniversityDepartment of Ophthalmology, The First Affiliated Hospital with Nanjing Medical UniversityMaternal and Child Healthcare Hospital of Yuhuatai DistrictMaternal and Child Healthcare Hospital of Yuhuatai DistrictMaternal and Child Healthcare Hospital of Yuhuatai DistrictNanjing Children’s HospitalDepartment of Ophthalmology, The First Affiliated Hospital with Nanjing Medical UniversityDepartment of Ophthalmology, The First Affiliated Hospital with Nanjing Medical UniversityAbstract This study evaluated the performance of plusoptiX A12C in detecting amblyopia risk factors (ARFs) in Chinese children aged 3-to-4-year. PlusoptiX examination was successfully conducted among 1,766 subjects without cycloplegia to detect refractive error, asymmetry and media opacity. Cycloplegic retinoscopy (CR) was conducted on 357 children suspected of having vision abnormalities. Statistical differences between CR and the device were confirmed using the mean spherical value (+1.41 ± 0.87 D versus +1.14 ± 0.81 D), cylindrical value (−0.47 ± 0.64 versus −0.84 ± 0.78) and spherical equivalent (SE) value (+1.17 ± 0.84 D versus +0.72 ± 0.64 D) (all P < 0.0001). In the emmetropia group, the differences were statistically significant for the cylinder and SE (all P < 0.0001) but not the sphere (P = 0.33). In the hyperopia group, the differences were statistically significant for the sphere, cylinder and SE (all P < 0.0001). For refractive and strabismic ARFs detection, the sensitivity, specificity, positive predictive value, and negative predictive value were calculated, respectively.https://doi.org/10.1038/s41598-017-02246-6
spellingShingle Dan Huang
Xuejuan Chen
Xiaohan Zhang
Yue Wang
Hui Zhu
Hui Ding
Jing Bai
Ji Chen
Zhujun Fu
Zijin Wang
Hu Liu
Pediatric vision screening using the plusoptiX A12C photoscreener in Chinese preschool children aged 3 to 4 years
Scientific Reports
title Pediatric vision screening using the plusoptiX A12C photoscreener in Chinese preschool children aged 3 to 4 years
title_full Pediatric vision screening using the plusoptiX A12C photoscreener in Chinese preschool children aged 3 to 4 years
title_fullStr Pediatric vision screening using the plusoptiX A12C photoscreener in Chinese preschool children aged 3 to 4 years
title_full_unstemmed Pediatric vision screening using the plusoptiX A12C photoscreener in Chinese preschool children aged 3 to 4 years
title_short Pediatric vision screening using the plusoptiX A12C photoscreener in Chinese preschool children aged 3 to 4 years
title_sort pediatric vision screening using the plusoptix a12c photoscreener in chinese preschool children aged 3 to 4 years
url https://doi.org/10.1038/s41598-017-02246-6
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