Factors Contributing to an Efficacious Endovascular Treatment for Acute Ischemic Stroke in Asian Population

Although randomized control trials about endovascular treatment (EVT) of emergent large vessel occlusion (LVO) have demonstrated the success of mechanical thrombectomy as the choice of treatment, a wide range of caveats remain unaddressed. Asian patients were rarely included in the trials, thereby r...

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Main Authors: Jin Soo Lee, Yang-Ha Hwang, Sung-Il Sohn
Format: Article
Language:English
Published: Korean Society of Interventional Neuroradiology 2021-07-01
Series:Neurointervention
Subjects:
Online Access:http://neurointervention.org/upload/pdf/neuroint-2020-00339.pdf
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author Jin Soo Lee
Yang-Ha Hwang
Sung-Il Sohn
author_facet Jin Soo Lee
Yang-Ha Hwang
Sung-Il Sohn
author_sort Jin Soo Lee
collection DOAJ
description Although randomized control trials about endovascular treatment (EVT) of emergent large vessel occlusion (LVO) have demonstrated the success of mechanical thrombectomy as the choice of treatment, a wide range of caveats remain unaddressed. Asian patients were rarely included in the trials, thereby raising the question of whether the treatment could be generalized. In addition, there remains a concern on the feasibility of the method with respect to its application against intracranial atherosclerosis (ICAS)-related LVO, frequently observed in the Asian population. It is important to include evidence on ICAS LVO from Asian countries in the future for a comprehensive understanding of LVO etiology. Besides the issues with EVT, prognostic concerns in diabetes patients, acute kidney injury following EVT, neuroprotective management against reperfusion injury, and other peri-EVT issues should be considered in clinical practice. In the current article, we present an in-depth review of the literature that revises information pertaining to such concerns.
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spelling doaj.art-357774dbaabf45aaa9146b4f988cd1d82024-02-02T05:37:05ZengKorean Society of Interventional NeuroradiologyNeurointervention2093-90432233-62732021-07-011629111010.5469/neuroint.2020.00339318Factors Contributing to an Efficacious Endovascular Treatment for Acute Ischemic Stroke in Asian PopulationJin Soo Lee0Yang-Ha Hwang1Sung-Il Sohn2 Department of Neurology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea Department of Neurology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea Department of Neurology, Keimyung University Dongsan Hospital, Kyemyung University School of Medicine, Daegu, KoreaAlthough randomized control trials about endovascular treatment (EVT) of emergent large vessel occlusion (LVO) have demonstrated the success of mechanical thrombectomy as the choice of treatment, a wide range of caveats remain unaddressed. Asian patients were rarely included in the trials, thereby raising the question of whether the treatment could be generalized. In addition, there remains a concern on the feasibility of the method with respect to its application against intracranial atherosclerosis (ICAS)-related LVO, frequently observed in the Asian population. It is important to include evidence on ICAS LVO from Asian countries in the future for a comprehensive understanding of LVO etiology. Besides the issues with EVT, prognostic concerns in diabetes patients, acute kidney injury following EVT, neuroprotective management against reperfusion injury, and other peri-EVT issues should be considered in clinical practice. In the current article, we present an in-depth review of the literature that revises information pertaining to such concerns.http://neurointervention.org/upload/pdf/neuroint-2020-00339.pdfcerebral infarctionendovascular proceduresintracranial atherosclerosisdiabetes mellitusacute kidney injuryreperfusion injury
spellingShingle Jin Soo Lee
Yang-Ha Hwang
Sung-Il Sohn
Factors Contributing to an Efficacious Endovascular Treatment for Acute Ischemic Stroke in Asian Population
Neurointervention
cerebral infarction
endovascular procedures
intracranial atherosclerosis
diabetes mellitus
acute kidney injury
reperfusion injury
title Factors Contributing to an Efficacious Endovascular Treatment for Acute Ischemic Stroke in Asian Population
title_full Factors Contributing to an Efficacious Endovascular Treatment for Acute Ischemic Stroke in Asian Population
title_fullStr Factors Contributing to an Efficacious Endovascular Treatment for Acute Ischemic Stroke in Asian Population
title_full_unstemmed Factors Contributing to an Efficacious Endovascular Treatment for Acute Ischemic Stroke in Asian Population
title_short Factors Contributing to an Efficacious Endovascular Treatment for Acute Ischemic Stroke in Asian Population
title_sort factors contributing to an efficacious endovascular treatment for acute ischemic stroke in asian population
topic cerebral infarction
endovascular procedures
intracranial atherosclerosis
diabetes mellitus
acute kidney injury
reperfusion injury
url http://neurointervention.org/upload/pdf/neuroint-2020-00339.pdf
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