An efficient synthesis of warfarin acetals on montmorillonite clay K-10 with microwaves

The microwave promoted reaction of warfarin with methanol, or ethanol, in the presence of montmorillonite clay K-10 as a catalyst, affords the corresponding acetals, 2-methoxy 2-methyl-4-phenyl-3,4-dihydro-2H-pyrano[3,2-c]chromen-5-one (2) and 2-ethoxy-2-methyl- 4-phenyl-3,4-dihydro-2H-pyrano[3,2-c]...

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Main Authors: Krstić Ljubomir, Sukdolak Slobodan, Solujić-Sukdolak Slavica
Format: Article
Language:English
Published: Serbian Chemical Society 2002-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2002/0352-51390205325K.pdf
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author Krstić Ljubomir
Sukdolak Slobodan
Solujić-Sukdolak Slavica
author_facet Krstić Ljubomir
Sukdolak Slobodan
Solujić-Sukdolak Slavica
author_sort Krstić Ljubomir
collection DOAJ
description The microwave promoted reaction of warfarin with methanol, or ethanol, in the presence of montmorillonite clay K-10 as a catalyst, affords the corresponding acetals, 2-methoxy 2-methyl-4-phenyl-3,4-dihydro-2H-pyrano[3,2-c]chromen-5-one (2) and 2-ethoxy-2-methyl- 4-phenyl-3,4-dihydro-2H-pyrano[3,2-c]chromen-5-one (3) respectively, in good yields.
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spelling doaj.art-357ae8a3846d4f47bec65d60ceb2dd0d2022-12-21T23:24:14ZengSerbian Chemical SocietyJournal of the Serbian Chemical Society0352-51391820-74212002-01-0167532532910.2298/JSC0205325K0352-51390205325KAn efficient synthesis of warfarin acetals on montmorillonite clay K-10 with microwavesKrstić Ljubomir0Sukdolak Slobodan1Solujić-Sukdolak Slavica2Institute of Chemistry, Technology and Metallurgy - Center of Chemistry, BelgradeFaculty of Sciences - Department of Chemistry, KragujevacFaculty of Sciences - Department of Chemistry, KragujevacThe microwave promoted reaction of warfarin with methanol, or ethanol, in the presence of montmorillonite clay K-10 as a catalyst, affords the corresponding acetals, 2-methoxy 2-methyl-4-phenyl-3,4-dihydro-2H-pyrano[3,2-c]chromen-5-one (2) and 2-ethoxy-2-methyl- 4-phenyl-3,4-dihydro-2H-pyrano[3,2-c]chromen-5-one (3) respectively, in good yields.http://www.doiserbia.nb.rs/img/doi/0352-5139/2002/0352-51390205325K.pdfwarfarincyclic acetalsmontmorillonite k-10microwaves.
spellingShingle Krstić Ljubomir
Sukdolak Slobodan
Solujić-Sukdolak Slavica
An efficient synthesis of warfarin acetals on montmorillonite clay K-10 with microwaves
Journal of the Serbian Chemical Society
warfarin
cyclic acetals
montmorillonite k-10
microwaves.
title An efficient synthesis of warfarin acetals on montmorillonite clay K-10 with microwaves
title_full An efficient synthesis of warfarin acetals on montmorillonite clay K-10 with microwaves
title_fullStr An efficient synthesis of warfarin acetals on montmorillonite clay K-10 with microwaves
title_full_unstemmed An efficient synthesis of warfarin acetals on montmorillonite clay K-10 with microwaves
title_short An efficient synthesis of warfarin acetals on montmorillonite clay K-10 with microwaves
title_sort efficient synthesis of warfarin acetals on montmorillonite clay k 10 with microwaves
topic warfarin
cyclic acetals
montmorillonite k-10
microwaves.
url http://www.doiserbia.nb.rs/img/doi/0352-5139/2002/0352-51390205325K.pdf
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