Pulmonary embolism and megaloblastic anemia: is there a link? A case report an literature review

Pulmonary embolism and megaloblastic anemia: is there a link? A case report an literature review

Many factors have been associated with venous thromboembolism. Among them, vitamin B12 deficiency can produce elevated homocysteine levels, which is a risk factor for venous embolism, since the latter interferes with the activation of Va coagulation factor by activation of C protein.We present a cas...

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Bibliographic Details
Main Authors: Grecia Iveth Raymundo-Martínez, MD, Rodrigo Gopar-Nieto, MD, Gonzalo Carazo-Vargas, MD, Diego Araiza-Garaygordobil, MD, Sergio Raul Scuri, MD, Laura Leticia Rodríguez-Chavez, MD, Nilda Espinola-Zavaleta, MD, PhD
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Radiology Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S1930043318302632
Description
Summary:Many factors have been associated with venous thromboembolism. Among them, vitamin B12 deficiency can produce elevated homocysteine levels, which is a risk factor for venous embolism, since the latter interferes with the activation of Va coagulation factor by activation of C protein.We present a case of a patient with metabolic syndrome with apparently unprovoked pulmonary embolism. After careful evaluation, megaloblastic anemia was detected. Even though the patient had biochemistry findings of hemolysis and blood smear did not showed fragmented erythrocytes, which is consistent with pseudo-microangiopathic hemolytic anemia. Keywords: Pulmonary embolism, Megaloblastic anemia, B12 deficiency
ISSN:1930-0433

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