Synthesizing, Structuring, and Characterizing Bioactivities of .Cr(III), La(III), and Ce(III) .Complexes with Nitrogen, Oxygen .and Sulpher donor bidentate Schiff base ligands
Two Schiff bases, namely, 3-(benzylidene amino) -2-thioxo-6-methyl 2,5-dihydropyrimidine-4(3H)-one (LS])and 3-(benzylidene amino)-6-methyl pyrimidine 4(3H, 5H)-dione(LA)as chelating ligands), were used to prepare some complexes of Cr(III), La(III), and Ce(III)] ions. Standard physico-chemical proced...
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| Format: | Article |
| Language: | Arabic |
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College of Science for Women, University of Baghdad
2021-12-01
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| Series: | Baghdad Science Journal |
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| Online Access: | https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/5618 |
| _version_ | 1811189658347896832 |
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| author | Anaam M. Rasheed Sinan M. M. Al-Bayati Dr.Rehab A.M. Al-Hasani Muna Ali Shakir |
| author_facet | Anaam M. Rasheed Sinan M. M. Al-Bayati Dr.Rehab A.M. Al-Hasani Muna Ali Shakir |
| author_sort | Anaam M. Rasheed |
| collection | DOAJ |
| description | Two Schiff bases, namely, 3-(benzylidene amino) -2-thioxo-6-methyl 2,5-dihydropyrimidine-4(3H)-one (LS])and 3-(benzylidene amino)-6-methyl pyrimidine 4(3H, 5H)-dione(LA)as chelating ligands), were used to prepare some complexes of Cr(III), La(III), and Ce(III)] ions. Standard physico-chemical procedures including metal analysis M%, element microanalysis (C.H.N.S) , magnetic susceptibility, conductometric measurements, FT-IR and UV-visible Spectra were used to identify Metal (III) complexes and Schiff bases (LS) and (LA). According to findings, a [Cr(III) complex] showed six coordinated octahedral geometry, while [La(III), and Ce(III) complexes]were structured with coordination number seven. Schiff's bases and mineral complexes were examined in vitro to investigate potential inhibition against Gram-positive bacteria such as Pseudonomous aerugionosa and Gram-negative bacteria such as Staphylococcus aureus. The low concentration for inhibition has been also determined by studying the minimal inhibitory concentrations MIC .Antibiotics (Ampicillin, Amoxicillin) have been chosen to contrast their activity. Furthermore, Anti-fungal activity against two types of fungi ʺAspergillus flavusʺ and ʺPenicillum Spp.ʺ was studied for these compounds. The results of the antibacterial activity were better compared to the standard drugs. |
| first_indexed | 2024-04-11T14:39:20Z |
| format | Article |
| id | doaj.art-357c5a6c31f94cffb4e86b5be66d0363 |
| institution | Directory Open Access Journal |
| issn | 2078-8665 2411-7986 |
| language | Arabic |
| last_indexed | 2024-04-11T14:39:20Z |
| publishDate | 2021-12-01 |
| publisher | College of Science for Women, University of Baghdad |
| record_format | Article |
| series | Baghdad Science Journal |
| spelling | doaj.art-357c5a6c31f94cffb4e86b5be66d03632022-12-22T04:18:06ZaraCollege of Science for Women, University of BaghdadBaghdad Science Journal2078-86652411-79862021-12-01184(Suppl.)10.21123/bsj.2021.18.4(Suppl.).1545Synthesizing, Structuring, and Characterizing Bioactivities of .Cr(III), La(III), and Ce(III) .Complexes with Nitrogen, Oxygen .and Sulpher donor bidentate Schiff base ligandsAnaam M. Rasheed0Sinan M. M. Al-Bayati1Dr.Rehab A.M. Al-Hasani2Muna Ali Shakir3Department of Chemistry, College of Science, Al- Mustansiriyah University, Baghdad, Iraq.Department of Chemistry, College of Science, Al- Mustansiriyah University, Baghdad, Iraq.Department of Chemistry, College of Science, Al- Mustansiriyah University, Baghdad, Iraq.Department of Chemistry, College of Science, Al- Mustansiriyah University, Baghdad, Iraq.Two Schiff bases, namely, 3-(benzylidene amino) -2-thioxo-6-methyl 2,5-dihydropyrimidine-4(3H)-one (LS])and 3-(benzylidene amino)-6-methyl pyrimidine 4(3H, 5H)-dione(LA)as chelating ligands), were used to prepare some complexes of Cr(III), La(III), and Ce(III)] ions. Standard physico-chemical procedures including metal analysis M%, element microanalysis (C.H.N.S) , magnetic susceptibility, conductometric measurements, FT-IR and UV-visible Spectra were used to identify Metal (III) complexes and Schiff bases (LS) and (LA). According to findings, a [Cr(III) complex] showed six coordinated octahedral geometry, while [La(III), and Ce(III) complexes]were structured with coordination number seven. Schiff's bases and mineral complexes were examined in vitro to investigate potential inhibition against Gram-positive bacteria such as Pseudonomous aerugionosa and Gram-negative bacteria such as Staphylococcus aureus. The low concentration for inhibition has been also determined by studying the minimal inhibitory concentrations MIC .Antibiotics (Ampicillin, Amoxicillin) have been chosen to contrast their activity. Furthermore, Anti-fungal activity against two types of fungi ʺAspergillus flavusʺ and ʺPenicillum Spp.ʺ was studied for these compounds. The results of the antibacterial activity were better compared to the standard drugs.https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/5618Antimicrobial activity, Complexes of Pyrimidine Derivatives, lanthanide Metal Complexes, Spectroscopic analysis, Transition Metal Complexes |
| spellingShingle | Anaam M. Rasheed Sinan M. M. Al-Bayati Dr.Rehab A.M. Al-Hasani Muna Ali Shakir Synthesizing, Structuring, and Characterizing Bioactivities of .Cr(III), La(III), and Ce(III) .Complexes with Nitrogen, Oxygen .and Sulpher donor bidentate Schiff base ligands Baghdad Science Journal Antimicrobial activity, Complexes of Pyrimidine Derivatives, lanthanide Metal Complexes, Spectroscopic analysis, Transition Metal Complexes |
| title | Synthesizing, Structuring, and Characterizing Bioactivities of .Cr(III), La(III), and Ce(III) .Complexes with Nitrogen, Oxygen .and Sulpher donor bidentate Schiff base ligands |
| title_full | Synthesizing, Structuring, and Characterizing Bioactivities of .Cr(III), La(III), and Ce(III) .Complexes with Nitrogen, Oxygen .and Sulpher donor bidentate Schiff base ligands |
| title_fullStr | Synthesizing, Structuring, and Characterizing Bioactivities of .Cr(III), La(III), and Ce(III) .Complexes with Nitrogen, Oxygen .and Sulpher donor bidentate Schiff base ligands |
| title_full_unstemmed | Synthesizing, Structuring, and Characterizing Bioactivities of .Cr(III), La(III), and Ce(III) .Complexes with Nitrogen, Oxygen .and Sulpher donor bidentate Schiff base ligands |
| title_short | Synthesizing, Structuring, and Characterizing Bioactivities of .Cr(III), La(III), and Ce(III) .Complexes with Nitrogen, Oxygen .and Sulpher donor bidentate Schiff base ligands |
| title_sort | synthesizing structuring and characterizing bioactivities of cr iii la iii and ce iii complexes with nitrogen oxygen and sulpher donor bidentate schiff base ligands |
| topic | Antimicrobial activity, Complexes of Pyrimidine Derivatives, lanthanide Metal Complexes, Spectroscopic analysis, Transition Metal Complexes |
| url | https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/5618 |
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