Risk Factors of Catheter-related Bloodstream Infection With Percutaneously Inserted Central Venous Catheters in Very Low Birth Weight Infants: A Center's Experience in Taiwan
Infected percutaneously inserted central venous catheters (PICCs) are a problem in hospitalized patients, especially in the neonatal intensive care unit. The objective of this study was to assess the risk of infection and other PICC-associated complications in very low birth weight infants. Methods:...
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| Format: | Article |
| Language: | English |
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Elsevier
2010-12-01
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| Series: | Pediatrics and Neonatology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1875957210600654 |
| _version_ | 1818399219277365248 |
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| author | Jen-Fu Hsu Ming-Horng Tsai Hsuan-Rong Huang Reyin Lien Shih-Ming Chu Chung-Bin Huang |
| author_facet | Jen-Fu Hsu Ming-Horng Tsai Hsuan-Rong Huang Reyin Lien Shih-Ming Chu Chung-Bin Huang |
| author_sort | Jen-Fu Hsu |
| collection | DOAJ |
| description | Infected percutaneously inserted central venous catheters (PICCs) are a problem in hospitalized patients, especially in the neonatal intensive care unit. The objective of this study was to assess the risk of infection and other PICC-associated complications in very low birth weight infants.
Methods: Between January 2005 and December 2006, we studied 412 PICCs inserted in 267 neonates with a birth body weight ≤ 1500g. PICC-related bloodstream infections and other complications were recorded and analyzed.
Results: These 412 PICCs were inserted for a mean duration of 16.6 ± 9.9 (SD) days. The most common catheter-related complications were catheter-related blood-stream infection (CRBSI; incidence: 8.3 per 1000 catheter days), followed by catheter occlusion (4.0 per 1000 catheter days), catheter site inflammation (3.5 per 1000 catheter days), and phlebitis (3.1 per 1000 catheter days). The most common pathogen of CRBSI was coagulase-negative staphylococcus (40.1%). Significant risk factors of CRBSI included catheters inserted at femoral sites (increased risk of CRBSI compared with nonfemoral catheters: 1.76; 95% confidence interval, 1.01–3.07, p = 0.045) and a longer duration of PICC placement (p < 0.001). A low birth body weight and gestational age were not found to significantly affect the risk of CRBSI.
Conclusion: It is important to avoid inserting a PICC at the femoral site. Strict catheter care protocol should also be applied to reduce local site bacterial colonization and removal of PICCs as soon as they are no longer essential for patient care to reduce the incidence of infection. |
| first_indexed | 2024-12-14T07:17:12Z |
| format | Article |
| id | doaj.art-357ca3e001aa486e8bad02964e20c86b |
| institution | Directory Open Access Journal |
| issn | 1875-9572 |
| language | English |
| last_indexed | 2024-12-14T07:17:12Z |
| publishDate | 2010-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj.art-357ca3e001aa486e8bad02964e20c86b2022-12-21T23:11:42ZengElsevierPediatrics and Neonatology1875-95722010-12-0151633634210.1016/S1875-9572(10)60065-4Risk Factors of Catheter-related Bloodstream Infection With Percutaneously Inserted Central Venous Catheters in Very Low Birth Weight Infants: A Center's Experience in TaiwanJen-Fu Hsu0Ming-Horng Tsai1Hsuan-Rong Huang2Reyin Lien3Shih-Ming Chu4Chung-Bin Huang5Division of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, TaiwanDivisions of Neonatology and Pediatric Hematology/Oncology, Department of Pediatrics, Chang Gung Memorial Hospital, Chiayi, TaiwanDivision of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, TaiwanDivision of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, TaiwanDivision of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, TaiwanDivision of Neonatology, Department of Pediatrics, Kuang Tien General Hospital, Taichung, TaiwanInfected percutaneously inserted central venous catheters (PICCs) are a problem in hospitalized patients, especially in the neonatal intensive care unit. The objective of this study was to assess the risk of infection and other PICC-associated complications in very low birth weight infants. Methods: Between January 2005 and December 2006, we studied 412 PICCs inserted in 267 neonates with a birth body weight ≤ 1500g. PICC-related bloodstream infections and other complications were recorded and analyzed. Results: These 412 PICCs were inserted for a mean duration of 16.6 ± 9.9 (SD) days. The most common catheter-related complications were catheter-related blood-stream infection (CRBSI; incidence: 8.3 per 1000 catheter days), followed by catheter occlusion (4.0 per 1000 catheter days), catheter site inflammation (3.5 per 1000 catheter days), and phlebitis (3.1 per 1000 catheter days). The most common pathogen of CRBSI was coagulase-negative staphylococcus (40.1%). Significant risk factors of CRBSI included catheters inserted at femoral sites (increased risk of CRBSI compared with nonfemoral catheters: 1.76; 95% confidence interval, 1.01–3.07, p = 0.045) and a longer duration of PICC placement (p < 0.001). A low birth body weight and gestational age were not found to significantly affect the risk of CRBSI. Conclusion: It is important to avoid inserting a PICC at the femoral site. Strict catheter care protocol should also be applied to reduce local site bacterial colonization and removal of PICCs as soon as they are no longer essential for patient care to reduce the incidence of infection.http://www.sciencedirect.com/science/article/pii/S1875957210600654catheter-related bloodstream infectionpercutaneously inserted central venous catheterphlebitissepticemiavery low birth weight |
| spellingShingle | Jen-Fu Hsu Ming-Horng Tsai Hsuan-Rong Huang Reyin Lien Shih-Ming Chu Chung-Bin Huang Risk Factors of Catheter-related Bloodstream Infection With Percutaneously Inserted Central Venous Catheters in Very Low Birth Weight Infants: A Center's Experience in Taiwan Pediatrics and Neonatology catheter-related bloodstream infection percutaneously inserted central venous catheter phlebitis septicemia very low birth weight |
| title | Risk Factors of Catheter-related Bloodstream Infection With Percutaneously Inserted Central Venous Catheters in Very Low Birth Weight Infants: A Center's Experience in Taiwan |
| title_full | Risk Factors of Catheter-related Bloodstream Infection With Percutaneously Inserted Central Venous Catheters in Very Low Birth Weight Infants: A Center's Experience in Taiwan |
| title_fullStr | Risk Factors of Catheter-related Bloodstream Infection With Percutaneously Inserted Central Venous Catheters in Very Low Birth Weight Infants: A Center's Experience in Taiwan |
| title_full_unstemmed | Risk Factors of Catheter-related Bloodstream Infection With Percutaneously Inserted Central Venous Catheters in Very Low Birth Weight Infants: A Center's Experience in Taiwan |
| title_short | Risk Factors of Catheter-related Bloodstream Infection With Percutaneously Inserted Central Venous Catheters in Very Low Birth Weight Infants: A Center's Experience in Taiwan |
| title_sort | risk factors of catheter related bloodstream infection with percutaneously inserted central venous catheters in very low birth weight infants a center s experience in taiwan |
| topic | catheter-related bloodstream infection percutaneously inserted central venous catheter phlebitis septicemia very low birth weight |
| url | http://www.sciencedirect.com/science/article/pii/S1875957210600654 |
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