Preoperative electrophysiological characterization of patients with primary macula-involving rhegmatogenous retinal detachment
Purpose: To determine 1) which components of retinal function are impaired after rhegmatogenous retinal detachment, 2) which outer retinal pathways (rod- or cone-driven) are more severely affected, and 3) whether there is concomitant inner retinal dysfunction. Methods: We conducted a prospective obs...
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| Format: | Article |
| Language: | English |
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Knowledge E
2018-01-01
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| Series: | Journal of Ophthalmic & Vision Research |
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| Online Access: | http://www.jovr.org/article.asp?issn=2008-322X;year=2018;volume=13;issue=3;spage=241;epage=248;aulast=Lin |
| _version_ | 1797991403110793216 |
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| author | Jonathan B Lin Julia Sein Gregory P Van Stavern Rajendra S Apte |
| author_facet | Jonathan B Lin Julia Sein Gregory P Van Stavern Rajendra S Apte |
| author_sort | Jonathan B Lin |
| collection | DOAJ |
| description | Purpose: To determine 1) which components of retinal function are impaired after rhegmatogenous retinal detachment, 2) which outer retinal pathways (rod- or cone-driven) are more severely affected, and 3) whether there is concomitant inner retinal dysfunction.
Methods: We conducted a prospective observational study in a large academic institution. We performed preoperative electroretinography on eight patients to assess outer and inner retinal function. In all cases, a comparison between the eye with the detached retina and the control fellow eye was made.
Results: Eyes with a detached retina had significantly lower a-wave and b-wave amplitudes with respect to both rod- and cone-dominated testing parameters (P < 0.05) and reduced 30 Hz flicker responses compared to fellow eyes (P < 0.05); the effect size was similar for all significantly reduced parameters (r~0.6). There were no significant differences between eyes with detached retinas and control fellow eyes with respect to b/a-wave ratios, a-wave latencies, or b-wave latencies.
Conclusion: Patients with rhegmatogenous retinal detachment have preoperative outer retinal dysfunction equally affecting both rod- and cone-driven pathways, and they have minimal inner retinal dysfunction. |
| first_indexed | 2024-04-11T08:51:41Z |
| format | Article |
| id | doaj.art-357d1496e3ca4e6ebc707cc77e1a3d7d |
| institution | Directory Open Access Journal |
| issn | 2008-322X |
| language | English |
| last_indexed | 2024-04-11T08:51:41Z |
| publishDate | 2018-01-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj.art-357d1496e3ca4e6ebc707cc77e1a3d7d2022-12-22T04:33:33ZengKnowledge EJournal of Ophthalmic & Vision Research2008-322X2018-01-0113324124810.4103/jovr.jovr_161_17Preoperative electrophysiological characterization of patients with primary macula-involving rhegmatogenous retinal detachmentJonathan B LinJulia SeinGregory P Van StavernRajendra S AptePurpose: To determine 1) which components of retinal function are impaired after rhegmatogenous retinal detachment, 2) which outer retinal pathways (rod- or cone-driven) are more severely affected, and 3) whether there is concomitant inner retinal dysfunction. Methods: We conducted a prospective observational study in a large academic institution. We performed preoperative electroretinography on eight patients to assess outer and inner retinal function. In all cases, a comparison between the eye with the detached retina and the control fellow eye was made. Results: Eyes with a detached retina had significantly lower a-wave and b-wave amplitudes with respect to both rod- and cone-dominated testing parameters (P < 0.05) and reduced 30 Hz flicker responses compared to fellow eyes (P < 0.05); the effect size was similar for all significantly reduced parameters (r~0.6). There were no significant differences between eyes with detached retinas and control fellow eyes with respect to b/a-wave ratios, a-wave latencies, or b-wave latencies. Conclusion: Patients with rhegmatogenous retinal detachment have preoperative outer retinal dysfunction equally affecting both rod- and cone-driven pathways, and they have minimal inner retinal dysfunction.http://www.jovr.org/article.asp?issn=2008-322X;year=2018;volume=13;issue=3;spage=241;epage=248;aulast=LinClinical Electrophysiology; Electroretinography; Retinal Detachment |
| spellingShingle | Jonathan B Lin Julia Sein Gregory P Van Stavern Rajendra S Apte Preoperative electrophysiological characterization of patients with primary macula-involving rhegmatogenous retinal detachment Journal of Ophthalmic & Vision Research Clinical Electrophysiology; Electroretinography; Retinal Detachment |
| title | Preoperative electrophysiological characterization of patients with primary macula-involving rhegmatogenous retinal detachment |
| title_full | Preoperative electrophysiological characterization of patients with primary macula-involving rhegmatogenous retinal detachment |
| title_fullStr | Preoperative electrophysiological characterization of patients with primary macula-involving rhegmatogenous retinal detachment |
| title_full_unstemmed | Preoperative electrophysiological characterization of patients with primary macula-involving rhegmatogenous retinal detachment |
| title_short | Preoperative electrophysiological characterization of patients with primary macula-involving rhegmatogenous retinal detachment |
| title_sort | preoperative electrophysiological characterization of patients with primary macula involving rhegmatogenous retinal detachment |
| topic | Clinical Electrophysiology; Electroretinography; Retinal Detachment |
| url | http://www.jovr.org/article.asp?issn=2008-322X;year=2018;volume=13;issue=3;spage=241;epage=248;aulast=Lin |
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