Prevalence of antibody against rabies among confined, free-roaming and stray dogs in a transit city of Nigeria
The prevalence of anti-glycoprotein antibodies against rabies virus is studied in the sera of confined, free-roaming and stray dogs in Ilorin, the capital city of Kwara State, Nigeria. A quantitative indirect enzyme-linked immuno-sorbent assay (i-ELISA) was used to detect rabies virus anti-glycoprot...
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| Format: | Article |
| Language: | English |
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Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. Caporale
2011-12-01
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| Series: | Veterinaria Italiana |
| Subjects: | |
| Online Access: | http://www.izs.it/vet_italiana/2011/47_4/453.pdf |
| _version_ | 1811268040387461120 |
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| author | Babasola O. Olugasa Julius O. Aiyedun Benjamin O. Emikpe |
| author_facet | Babasola O. Olugasa Julius O. Aiyedun Benjamin O. Emikpe |
| author_sort | Babasola O. Olugasa |
| collection | DOAJ |
| description | The prevalence of anti-glycoprotein antibodies against rabies virus is studied in the sera of confined, free-roaming and stray dogs in Ilorin, the capital city of Kwara State, Nigeria. A quantitative indirect enzyme-linked immuno-sorbent assay (i-ELISA) was used to detect rabies virus anti-glycoprotein antibodies in sera from 116 confined, 61 free-roaming, and 13 stray dogs. The sera were collected between June and December 2008 from apparently healthy dogs. Of these 190 dogs, 81 (42.6%), consisting of 57 confined (49.1%), 23 free-roaming (37.7%) and 1 stray (7.7%), had antibody titres that exceeded the positive threshold of 0.5 equivalent units (eu)/ml against rabies, while 109 (57.4%) presented titres that were below the threshold. Prevalence of rabies anti-glycoprotein antibody was higher in the confined dogs compared to free-roaming and stray dogs. Our results indicated low anti-rabies sero-prevalence (42.6%) in the dog population of Ilorin, a transit city that lies between northern and southern Nigeria. This is the first community-based prevalence report on the anti-rabies serological profile of dogs in Nigeria. The need for primary and booster mass vaccination of dogs and the impact of these findings on rabies control in Nigeria are discussed. |
| first_indexed | 2024-04-12T21:14:52Z |
| format | Article |
| id | doaj.art-357dd4f87d68411f8dd21307dc30f5aa |
| institution | Directory Open Access Journal |
| issn | 0505-401X 1828-1427 |
| language | English |
| last_indexed | 2024-04-12T21:14:52Z |
| publishDate | 2011-12-01 |
| publisher | Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. Caporale |
| record_format | Article |
| series | Veterinaria Italiana |
| spelling | doaj.art-357dd4f87d68411f8dd21307dc30f5aa2022-12-22T03:16:29ZengIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. CaporaleVeterinaria Italiana0505-401X1828-14272011-12-01474453460Prevalence of antibody against rabies among confined, free-roaming and stray dogs in a transit city of NigeriaBabasola O. OlugasaJulius O. AiyedunBenjamin O. EmikpeThe prevalence of anti-glycoprotein antibodies against rabies virus is studied in the sera of confined, free-roaming and stray dogs in Ilorin, the capital city of Kwara State, Nigeria. A quantitative indirect enzyme-linked immuno-sorbent assay (i-ELISA) was used to detect rabies virus anti-glycoprotein antibodies in sera from 116 confined, 61 free-roaming, and 13 stray dogs. The sera were collected between June and December 2008 from apparently healthy dogs. Of these 190 dogs, 81 (42.6%), consisting of 57 confined (49.1%), 23 free-roaming (37.7%) and 1 stray (7.7%), had antibody titres that exceeded the positive threshold of 0.5 equivalent units (eu)/ml against rabies, while 109 (57.4%) presented titres that were below the threshold. Prevalence of rabies anti-glycoprotein antibody was higher in the confined dogs compared to free-roaming and stray dogs. Our results indicated low anti-rabies sero-prevalence (42.6%) in the dog population of Ilorin, a transit city that lies between northern and southern Nigeria. This is the first community-based prevalence report on the anti-rabies serological profile of dogs in Nigeria. The need for primary and booster mass vaccination of dogs and the impact of these findings on rabies control in Nigeria are discussed.http://www.izs.it/vet_italiana/2011/47_4/453.pdfAntibodyAnti-glycoprotein antibodyDogELISAEnzyme-linked immunosorbent assayIndirect ELISANigeriaRabiesVirus |
| spellingShingle | Babasola O. Olugasa Julius O. Aiyedun Benjamin O. Emikpe Prevalence of antibody against rabies among confined, free-roaming and stray dogs in a transit city of Nigeria Veterinaria Italiana Antibody Anti-glycoprotein antibody Dog ELISA Enzyme-linked immunosorbent assay Indirect ELISA Nigeria Rabies Virus |
| title | Prevalence of antibody against rabies among confined, free-roaming and stray dogs in a transit city of Nigeria |
| title_full | Prevalence of antibody against rabies among confined, free-roaming and stray dogs in a transit city of Nigeria |
| title_fullStr | Prevalence of antibody against rabies among confined, free-roaming and stray dogs in a transit city of Nigeria |
| title_full_unstemmed | Prevalence of antibody against rabies among confined, free-roaming and stray dogs in a transit city of Nigeria |
| title_short | Prevalence of antibody against rabies among confined, free-roaming and stray dogs in a transit city of Nigeria |
| title_sort | prevalence of antibody against rabies among confined free roaming and stray dogs in a transit city of nigeria |
| topic | Antibody Anti-glycoprotein antibody Dog ELISA Enzyme-linked immunosorbent assay Indirect ELISA Nigeria Rabies Virus |
| url | http://www.izs.it/vet_italiana/2011/47_4/453.pdf |
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