Kinin and Purine Signaling Contributes to Neuroblastoma Metastasis

Kinin and Purine Signaling Contributes to Neuroblastoma Metastasis

Bone marrow metastasis occurs in approximately 350,000 patients that annually die in the U.S. alone. In view of the importance of tumor cell migration into the bone marrow, we have here investigated effects of various concentrations of stromal cell-derived factor-1 (SDF-1), bradykinin- and ATP on bo...

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Bibliographic Details
Main Authors: Henning Ulrich, Mariusz Z. Ratajczak, Gabriela Schneider, Elena Adinolfi, Elisa Orioli, Enéas G. Ferrazoli, Talita Glaser, Juliana Corrêa-Velloso, Poliana C. M. Martins, Fernanda Coutinho, Ana P. J. Santos, Micheli M. Pillat, Ulrich Sack, Claudiana Lameu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pharmacology
Subjects:
metastasis
bradykinin
neuroblastoma
purinergic system
bone marrow
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00500/full

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