Role of Apparent Diffusion Coefficient in Characterisation of Neck MassesA Cross-sectional Study
Introduction: Neck masses are frequently encountered in clinical practice and differential diagnoses of a patient presenting with a neck mass is wide. Diffusion-Weighted Magnetic Resonance Imaging (DW-MRI) is an imaging technique based on molecular diffusion. It is a very helpful complementary t...
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JCDR Research and Publications Pvt. Ltd.
2021-10-01
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| Series: | International Journal of Anatomy Radiology and Surgery |
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| Online Access: | http://www.ijars.net/articles/PDF/2709/49273_CE[Ra1]_F(SHU)_PF1(SC_SHU)_PFA_NC_SC_PN(KM).pdf |
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| author | AMANDEEP SINGH BHAVDEEP MANGAT ARVINDER SINGH SOOD JASMIN PUREWAL GAURAVDEEP SINGH |
| author_facet | AMANDEEP SINGH BHAVDEEP MANGAT ARVINDER SINGH SOOD JASMIN PUREWAL GAURAVDEEP SINGH |
| author_sort | AMANDEEP SINGH |
| collection | DOAJ |
| description | Introduction: Neck masses are frequently encountered in clinical
practice and differential diagnoses of a patient presenting with a neck
mass is wide. Diffusion-Weighted Magnetic Resonance Imaging
(DW-MRI) is an imaging technique based on molecular diffusion. It is
a very helpful complementary technique in distinguishing neoplastic
from non neoplastic tissue and has numerous applications in the
evaluation of head and neck masses especially in head and neck
lymphadenopathy.
Aim: To evaluate the accuracy of Apparent Diffusion Coefficient
(ADC) in differentiating benign and malignant neck masses.
Materials and Methods: A single-centre cross-sectional study
comprising of 50 patients of all age groups with clinical suspicion
of neck swelling was conducted in Department of Radiodiagnosis
at Sri Guru Ram Das Institute of Medical Sciences and Research,
Amritsar, Punjab, India from March 2018 to February 2020.
All patients included were subjected to general physical and
detailed local examination. MRI was carried out on 1.5 Tesla Unit
On Philips Intera Achieva using Sense Body Coil with b factor of
0 and 1000 s/mm² and ADC maps were generated and the results
were compared with histopathological results and/or follow-up.
Statistical assessment was carried out using Statistical Package
for the Social Sciences (SPSS) version 24.0. Qualitative data
were compared using the Chi-square test.
Results: The most common cause of neck mass was lymph
nodal masses (18%) with highest numbers of patients in age
group 40-60 years (34%). When a cut-off ADC value of 1.1×10-3 s/
mm² was used, sensitivity of 95.23% and specificity of 89.65%
were obtained for characterisation of malignant lesions which
was statistically significant. There was a strong agreement
(k value=0.838) in diagnosing the nature of lesion using ADC
value on MRI with histopathological findings.
Conclusion: Diffusion Weighted Imaging (DWI) and ADC values
are new promising aspect of MRI and can help in differentiating
the nature of the neck lesions. DWI can readily differentiate
between benign and malignant lesions of neck with good efficacy
and reproducibility. |
| first_indexed | 2024-12-18T05:27:07Z |
| format | Article |
| id | doaj.art-357eecc618b7469d874b50c68df60d33 |
| institution | Directory Open Access Journal |
| issn | 2277-8543 2455-6874 |
| language | English |
| last_indexed | 2024-12-18T05:27:07Z |
| publishDate | 2021-10-01 |
| publisher | JCDR Research and Publications Pvt. Ltd. |
| record_format | Article |
| series | International Journal of Anatomy Radiology and Surgery |
| spelling | doaj.art-357eecc618b7469d874b50c68df60d332022-12-21T21:19:31ZengJCDR Research and Publications Pvt. Ltd.International Journal of Anatomy Radiology and Surgery2277-85432455-68742021-10-011004202410.7860/IJARS/2021/49273.2709Role of Apparent Diffusion Coefficient in Characterisation of Neck MassesA Cross-sectional StudyAMANDEEP SINGH0BHAVDEEP MANGAT1ARVINDER SINGH SOOD2JASMIN PUREWAL3GAURAVDEEP SINGH4Professor, Department of Radiology, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India.Consultant, Department of Radiology, SGL Hospital Mustafabad, Jalandhar, Punjab, India.Professor and Head, Department of ENT, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India.Resident, Department of Radiology, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India.Resident, Department of Radiology, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, IndiaIntroduction: Neck masses are frequently encountered in clinical practice and differential diagnoses of a patient presenting with a neck mass is wide. Diffusion-Weighted Magnetic Resonance Imaging (DW-MRI) is an imaging technique based on molecular diffusion. It is a very helpful complementary technique in distinguishing neoplastic from non neoplastic tissue and has numerous applications in the evaluation of head and neck masses especially in head and neck lymphadenopathy. Aim: To evaluate the accuracy of Apparent Diffusion Coefficient (ADC) in differentiating benign and malignant neck masses. Materials and Methods: A single-centre cross-sectional study comprising of 50 patients of all age groups with clinical suspicion of neck swelling was conducted in Department of Radiodiagnosis at Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India from March 2018 to February 2020. All patients included were subjected to general physical and detailed local examination. MRI was carried out on 1.5 Tesla Unit On Philips Intera Achieva using Sense Body Coil with b factor of 0 and 1000 s/mm² and ADC maps were generated and the results were compared with histopathological results and/or follow-up. Statistical assessment was carried out using Statistical Package for the Social Sciences (SPSS) version 24.0. Qualitative data were compared using the Chi-square test. Results: The most common cause of neck mass was lymph nodal masses (18%) with highest numbers of patients in age group 40-60 years (34%). When a cut-off ADC value of 1.1×10-3 s/ mm² was used, sensitivity of 95.23% and specificity of 89.65% were obtained for characterisation of malignant lesions which was statistically significant. There was a strong agreement (k value=0.838) in diagnosing the nature of lesion using ADC value on MRI with histopathological findings. Conclusion: Diffusion Weighted Imaging (DWI) and ADC values are new promising aspect of MRI and can help in differentiating the nature of the neck lesions. DWI can readily differentiate between benign and malignant lesions of neck with good efficacy and reproducibility.http://www.ijars.net/articles/PDF/2709/49273_CE[Ra1]_F(SHU)_PF1(SC_SHU)_PFA_NC_SC_PN(KM).pdfhodgkins lymphomaludwig’s anginamesenchymal tumourplunging ranula |
| spellingShingle | AMANDEEP SINGH BHAVDEEP MANGAT ARVINDER SINGH SOOD JASMIN PUREWAL GAURAVDEEP SINGH Role of Apparent Diffusion Coefficient in Characterisation of Neck MassesA Cross-sectional Study International Journal of Anatomy Radiology and Surgery hodgkins lymphoma ludwig’s angina mesenchymal tumour plunging ranula |
| title | Role of Apparent Diffusion Coefficient in Characterisation of Neck MassesA Cross-sectional Study |
| title_full | Role of Apparent Diffusion Coefficient in Characterisation of Neck MassesA Cross-sectional Study |
| title_fullStr | Role of Apparent Diffusion Coefficient in Characterisation of Neck MassesA Cross-sectional Study |
| title_full_unstemmed | Role of Apparent Diffusion Coefficient in Characterisation of Neck MassesA Cross-sectional Study |
| title_short | Role of Apparent Diffusion Coefficient in Characterisation of Neck MassesA Cross-sectional Study |
| title_sort | role of apparent diffusion coefficient in characterisation of neck massesa cross sectional study |
| topic | hodgkins lymphoma ludwig’s angina mesenchymal tumour plunging ranula |
| url | http://www.ijars.net/articles/PDF/2709/49273_CE[Ra1]_F(SHU)_PF1(SC_SHU)_PFA_NC_SC_PN(KM).pdf |
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