Case Series of End-Stage Liver Disease Patients with Severe Coccidioidomycosis
Liver disease causes relative compromise of the host immune system through multiple overlapping mechanisms and is an established risk factor for invasive fungal diseases including candidiasis and cryptococcosis. This immunologic derangement also leads to rapid progression of disease with resultant i...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-02-01
|
| Series: | Journal of Fungi |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2309-608X/9/3/305 |
| _version_ | 1797610788251238400 |
|---|---|
| author | Daniel Ho Kristen D. Kelley Satya Dandekar Stuart H. Cohen George R. Thompson |
| author_facet | Daniel Ho Kristen D. Kelley Satya Dandekar Stuart H. Cohen George R. Thompson |
| author_sort | Daniel Ho |
| collection | DOAJ |
| description | Liver disease causes relative compromise of the host immune system through multiple overlapping mechanisms and is an established risk factor for invasive fungal diseases including candidiasis and cryptococcosis. This immunologic derangement also leads to rapid progression of disease with resultant increases in morbidity and mortality. We describe severe coccidioidomycosis cases in the setting of liver dysfunction. Collaborative multi-center epidemiologic studies should be performed to determine the incidence of severe coccidioidomycosis in patients with concurrent liver disease. |
| first_indexed | 2024-03-11T06:19:56Z |
| format | Article |
| id | doaj.art-358367ccfa4b4e669504e44591974fa2 |
| institution | Directory Open Access Journal |
| issn | 2309-608X |
| language | English |
| last_indexed | 2024-03-11T06:19:56Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Fungi |
| spelling | doaj.art-358367ccfa4b4e669504e44591974fa22023-11-17T11:59:42ZengMDPI AGJournal of Fungi2309-608X2023-02-019330510.3390/jof9030305Case Series of End-Stage Liver Disease Patients with Severe CoccidioidomycosisDaniel Ho0Kristen D. Kelley1Satya Dandekar2Stuart H. Cohen3George R. Thompson4Department of Internal Medicine, University of California Davis, Sacramento, CA 95817, USADepartment of Internal Medicine, University of California Davis, Sacramento, CA 95817, USADepartment of Medical Microbiology and Immunology, University of California Davis, Davis, CA 95616, USADepartment of Internal Medicine, Division of Infectious Diseases, University of California Davis, Sacramento, CA 95817, USADepartment of Medical Microbiology and Immunology, University of California Davis, Davis, CA 95616, USALiver disease causes relative compromise of the host immune system through multiple overlapping mechanisms and is an established risk factor for invasive fungal diseases including candidiasis and cryptococcosis. This immunologic derangement also leads to rapid progression of disease with resultant increases in morbidity and mortality. We describe severe coccidioidomycosis cases in the setting of liver dysfunction. Collaborative multi-center epidemiologic studies should be performed to determine the incidence of severe coccidioidomycosis in patients with concurrent liver disease.https://www.mdpi.com/2309-608X/9/3/305liver diseasehepatitis<i>Coccidioides</i>mortality |
| spellingShingle | Daniel Ho Kristen D. Kelley Satya Dandekar Stuart H. Cohen George R. Thompson Case Series of End-Stage Liver Disease Patients with Severe Coccidioidomycosis Journal of Fungi liver disease hepatitis <i>Coccidioides</i> mortality |
| title | Case Series of End-Stage Liver Disease Patients with Severe Coccidioidomycosis |
| title_full | Case Series of End-Stage Liver Disease Patients with Severe Coccidioidomycosis |
| title_fullStr | Case Series of End-Stage Liver Disease Patients with Severe Coccidioidomycosis |
| title_full_unstemmed | Case Series of End-Stage Liver Disease Patients with Severe Coccidioidomycosis |
| title_short | Case Series of End-Stage Liver Disease Patients with Severe Coccidioidomycosis |
| title_sort | case series of end stage liver disease patients with severe coccidioidomycosis |
| topic | liver disease hepatitis <i>Coccidioides</i> mortality |
| url | https://www.mdpi.com/2309-608X/9/3/305 |
| work_keys_str_mv | AT danielho caseseriesofendstageliverdiseasepatientswithseverecoccidioidomycosis AT kristendkelley caseseriesofendstageliverdiseasepatientswithseverecoccidioidomycosis AT satyadandekar caseseriesofendstageliverdiseasepatientswithseverecoccidioidomycosis AT stuarthcohen caseseriesofendstageliverdiseasepatientswithseverecoccidioidomycosis AT georgerthompson caseseriesofendstageliverdiseasepatientswithseverecoccidioidomycosis |