Somatostatin receptor based hybrid imaging in sarcoidosis

Abstract Several diagnostic imaging methodologies are available for the clinical evaluation of sarcoidosis, but all have their limitations. FDG PET/CT is frequently used, but this technique does not provide optimal results in all cases. Novel radiopharmaceuticals aimed at other disease targets may b...

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Main Authors: Riemer H. J. A. Slart, Klaas-Pieter Koopmans, Peter Paul van Geel, Henk Kramer, Harry J. M. Groen, C. Tji-Joong Gan, Niek H. J. Prakken, Andor W. J. M. Glaudemans, George D. Nossent
Format: Article
Language:English
Published: SpringerOpen 2017-12-01
Series:European Journal of Hybrid Imaging
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Online Access:http://link.springer.com/article/10.1186/s41824-017-0014-y
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author Riemer H. J. A. Slart
Klaas-Pieter Koopmans
Peter Paul van Geel
Henk Kramer
Harry J. M. Groen
C. Tji-Joong Gan
Niek H. J. Prakken
Andor W. J. M. Glaudemans
George D. Nossent
author_facet Riemer H. J. A. Slart
Klaas-Pieter Koopmans
Peter Paul van Geel
Henk Kramer
Harry J. M. Groen
C. Tji-Joong Gan
Niek H. J. Prakken
Andor W. J. M. Glaudemans
George D. Nossent
author_sort Riemer H. J. A. Slart
collection DOAJ
description Abstract Several diagnostic imaging methodologies are available for the clinical evaluation of sarcoidosis, but all have their limitations. FDG PET/CT is frequently used, but this technique does not provide optimal results in all cases. Novel radiopharmaceuticals aimed at other disease targets may be helpful, particularly in cardiac sarcoidosis when FDG PET/CT has a low diagnostic accuracy, due to difficulties in preparing the patients who should use a specific diet combined with prolonged fasting. 68Ga-labeled somatostatin based receptor hybrid imaging is a potential alternative to FDG PET/CT. This short communication provides a rapid overview of initial findings concerning the application of 68Ga-labeled somatostatin based receptor hybrid imaging in the diagnosis of (cardiac) sarcoidosis activity.
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spelling doaj.art-35869e3375e3453ba54703fac39652092022-12-22T02:16:15ZengSpringerOpenEuropean Journal of Hybrid Imaging2510-36362017-12-01111510.1186/s41824-017-0014-ySomatostatin receptor based hybrid imaging in sarcoidosisRiemer H. J. A. Slart0Klaas-Pieter Koopmans1Peter Paul van Geel2Henk Kramer3Harry J. M. Groen4C. Tji-Joong Gan5Niek H. J. Prakken6Andor W. J. M. Glaudemans7George D. Nossent8Medical Imaging Center (MIC), Department of Nuclear Medicine & Molecular Imaging and Radiology, University of Groningen, University Medical Center GroningenDepartment of Nuclear Medicine and Radiology, Martini HospitalDepartment of CardiologyDepartment of Pulmonology, Martini HospitalDepartment of Pulmonology, University of Groningen, University Medical Center GroningenDepartment of Pulmonology, University of Groningen, University Medical Center GroningenMedical Imaging Center (MIC), Department of Nuclear Medicine & Molecular Imaging and Radiology, University of Groningen, University Medical Center GroningenMedical Imaging Center (MIC), Department of Nuclear Medicine & Molecular Imaging and Radiology, University of Groningen, University Medical Center GroningenDepartment of Pulmonology, University of Groningen, University Medical Center GroningenAbstract Several diagnostic imaging methodologies are available for the clinical evaluation of sarcoidosis, but all have their limitations. FDG PET/CT is frequently used, but this technique does not provide optimal results in all cases. Novel radiopharmaceuticals aimed at other disease targets may be helpful, particularly in cardiac sarcoidosis when FDG PET/CT has a low diagnostic accuracy, due to difficulties in preparing the patients who should use a specific diet combined with prolonged fasting. 68Ga-labeled somatostatin based receptor hybrid imaging is a potential alternative to FDG PET/CT. This short communication provides a rapid overview of initial findings concerning the application of 68Ga-labeled somatostatin based receptor hybrid imaging in the diagnosis of (cardiac) sarcoidosis activity.http://link.springer.com/article/10.1186/s41824-017-0014-ySarcoidosisCardiacPET/CTSomatostatin receptor imaging
spellingShingle Riemer H. J. A. Slart
Klaas-Pieter Koopmans
Peter Paul van Geel
Henk Kramer
Harry J. M. Groen
C. Tji-Joong Gan
Niek H. J. Prakken
Andor W. J. M. Glaudemans
George D. Nossent
Somatostatin receptor based hybrid imaging in sarcoidosis
European Journal of Hybrid Imaging
Sarcoidosis
Cardiac
PET/CT
Somatostatin receptor imaging
title Somatostatin receptor based hybrid imaging in sarcoidosis
title_full Somatostatin receptor based hybrid imaging in sarcoidosis
title_fullStr Somatostatin receptor based hybrid imaging in sarcoidosis
title_full_unstemmed Somatostatin receptor based hybrid imaging in sarcoidosis
title_short Somatostatin receptor based hybrid imaging in sarcoidosis
title_sort somatostatin receptor based hybrid imaging in sarcoidosis
topic Sarcoidosis
Cardiac
PET/CT
Somatostatin receptor imaging
url http://link.springer.com/article/10.1186/s41824-017-0014-y
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AT harryjmgroen somatostatinreceptorbasedhybridimaginginsarcoidosis
AT ctjijoonggan somatostatinreceptorbasedhybridimaginginsarcoidosis
AT niekhjprakken somatostatinreceptorbasedhybridimaginginsarcoidosis
AT andorwjmglaudemans somatostatinreceptorbasedhybridimaginginsarcoidosis
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