SELECTIVE INTRA-ARTERIAL CHEMOTHERAPY (IAC) IN TREATMENT AT CHILDREN WITH THE INTRAOCULAR RETYNOBLASTOMA

Treatment of intraocular retinoblastoma is challenging. It requires a multidisciplinary personalized approach that includes focal treatments, chemotherapy, surgery and radiotherapy. Today, the focus of therapy has shifted to eye preservation with the major aim to save the child’s life and to preserv...

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Main Author: I. V. Pogrebnyakov
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2018-03-01
Series:Сибирский онкологический журнал
Subjects:
Online Access:https://www.siboncoj.ru/jour/article/view/673
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author I. V. Pogrebnyakov
author_facet I. V. Pogrebnyakov
author_sort I. V. Pogrebnyakov
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description Treatment of intraocular retinoblastoma is challenging. It requires a multidisciplinary personalized approach that includes focal treatments, chemotherapy, surgery and radiotherapy. Today, the focus of therapy has shifted to eye preservation with the major aim to save the child’s life and to preserve the eyeball as a functioning organ of vision with minimal complications. One of the most promising therapy approaches is selective intra-arterial chemotherapy (IAC), by which a cytostatic agent is given directly into the eye. This treatment modality has been shown to provide survival benefit and improvement of quality of life, reducing toxicity and minimizing side effects.
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spelling doaj.art-3589449523dd40458f02d3f9c766551b2023-03-13T09:05:51ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682018-03-01171647110.21294/1814-4861-2018-17-1-64-71518SELECTIVE INTRA-ARTERIAL CHEMOTHERAPY (IAC) IN TREATMENT AT CHILDREN WITH THE INTRAOCULAR RETYNOBLASTOMAI. V. Pogrebnyakov0НИИ клинической и экспериментальной радиологии ФГБУ «Национальный медицинский исследовательский центр им. Н.Н. Блохина» Минздрава РоссииTreatment of intraocular retinoblastoma is challenging. It requires a multidisciplinary personalized approach that includes focal treatments, chemotherapy, surgery and radiotherapy. Today, the focus of therapy has shifted to eye preservation with the major aim to save the child’s life and to preserve the eyeball as a functioning organ of vision with minimal complications. One of the most promising therapy approaches is selective intra-arterial chemotherapy (IAC), by which a cytostatic agent is given directly into the eye. This treatment modality has been shown to provide survival benefit and improvement of quality of life, reducing toxicity and minimizing side effects.https://www.siboncoj.ru/jour/article/view/673ретинобластомаорганосохраняющее лечениеселективная интраартериальная химиотерапия (сиахт)интравитреальная химиотерапия
spellingShingle I. V. Pogrebnyakov
SELECTIVE INTRA-ARTERIAL CHEMOTHERAPY (IAC) IN TREATMENT AT CHILDREN WITH THE INTRAOCULAR RETYNOBLASTOMA
Сибирский онкологический журнал
ретинобластома
органосохраняющее лечение
селективная интраартериальная химиотерапия (сиахт)
интравитреальная химиотерапия
title SELECTIVE INTRA-ARTERIAL CHEMOTHERAPY (IAC) IN TREATMENT AT CHILDREN WITH THE INTRAOCULAR RETYNOBLASTOMA
title_full SELECTIVE INTRA-ARTERIAL CHEMOTHERAPY (IAC) IN TREATMENT AT CHILDREN WITH THE INTRAOCULAR RETYNOBLASTOMA
title_fullStr SELECTIVE INTRA-ARTERIAL CHEMOTHERAPY (IAC) IN TREATMENT AT CHILDREN WITH THE INTRAOCULAR RETYNOBLASTOMA
title_full_unstemmed SELECTIVE INTRA-ARTERIAL CHEMOTHERAPY (IAC) IN TREATMENT AT CHILDREN WITH THE INTRAOCULAR RETYNOBLASTOMA
title_short SELECTIVE INTRA-ARTERIAL CHEMOTHERAPY (IAC) IN TREATMENT AT CHILDREN WITH THE INTRAOCULAR RETYNOBLASTOMA
title_sort selective intra arterial chemotherapy iac in treatment at children with the intraocular retynoblastoma
topic ретинобластома
органосохраняющее лечение
селективная интраартериальная химиотерапия (сиахт)
интравитреальная химиотерапия
url https://www.siboncoj.ru/jour/article/view/673
work_keys_str_mv AT ivpogrebnyakov selectiveintraarterialchemotherapyiacintreatmentatchildrenwiththeintraocularretynoblastoma