Frequency of COVID‐19 vaccine side effects and its associated factors among the vaccinated population of Pakistan: A cross‐sectional study
Abstract Background Coronavirus disease 2019 (COVID‐19) vaccine side effects have an important role in the hesitancy of the general population toward vaccine administration. Therefore, this study was conducted to document the COVID‐19 vaccine side effects in our population. Materials and Methods An...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Health Science Reports |
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| Online Access: | https://doi.org/10.1002/hsr2.1071 |
| _version_ | 1797737767434715136 |
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| author | Farah Yasmin Hala Najeeb Hasan Fareed Siddiqui Muhammad Sohaib Asghar Hashir Ali Awan Rana Muhammad Usama Zoha Allahuddin Muhammad Junaid Tahir Kaleem Ullah Mohammed Mahmmoud Fadelallah Eljack |
| author_facet | Farah Yasmin Hala Najeeb Hasan Fareed Siddiqui Muhammad Sohaib Asghar Hashir Ali Awan Rana Muhammad Usama Zoha Allahuddin Muhammad Junaid Tahir Kaleem Ullah Mohammed Mahmmoud Fadelallah Eljack |
| author_sort | Farah Yasmin |
| collection | DOAJ |
| description | Abstract Background Coronavirus disease 2019 (COVID‐19) vaccine side effects have an important role in the hesitancy of the general population toward vaccine administration. Therefore, this study was conducted to document the COVID‐19 vaccine side effects in our population. Materials and Methods An online survey‐based, cross‐sectional study was carried out from September 1, 2021, to October 1, 2021, to document the side effects of the COVID‐19 vaccine among the general public. The questionnaire included participants’ sociodemographic data, type of vaccine, comorbidities, previous COVID‐19 infection, and assessment of side effects reported by them. Results The majority of the participants were <20 years of age (62.2%), females (74.9%), belonged to the educational sector (58.1%), residents of Sindh (65.7%), and were previously unaffected by COVID‐19 infection (73.3%). Sinovac (38.7%) followed by Sinopharm (30.4%) and Moderna (18.4%) were administered more frequently. Commonly reported side effects were injection site pain (82%), myalgia (55%), headache (46%), fatigue/malaise (45%), and fever (41%). Vaccine side effects were more likely to be reported with the first dose as compared to the second dose. On regression analysis, factors associated with occurrence of side effects included younger age (odds ratio [OR]: 6.000 [2.065–17.431], p < 0.001), female gender (OR: 2.373 [1.146–4.914], p = 0.020), marital status (OR: 0.217 [0.085–0.556], p < 0.001), graduate level of education (OR: 0.353 [0.153–0.816], p = 0.015), and occupation being either retired, freelancers, or social workers (OR: 0.310 [0.106–0.909]), p = 0.033). Previous infection with COVID‐19 (p = 0.458) and comorbidities were found unrelated (p = 0.707) to the occurrence of side effects. Conclusion The overall prevalence of local side effects was quite higher than the systemic ones. Further large‐scale studies on vaccine safety are required to strengthen public confidence in the vaccination drive. |
| first_indexed | 2024-03-12T13:33:08Z |
| format | Article |
| id | doaj.art-358b93475559419e9fe3daa7a9a1ae7c |
| institution | Directory Open Access Journal |
| issn | 2398-8835 |
| language | English |
| last_indexed | 2024-03-12T13:33:08Z |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Health Science Reports |
| spelling | doaj.art-358b93475559419e9fe3daa7a9a1ae7c2023-08-24T06:32:46ZengWileyHealth Science Reports2398-88352023-01-0161n/an/a10.1002/hsr2.1071Frequency of COVID‐19 vaccine side effects and its associated factors among the vaccinated population of Pakistan: A cross‐sectional studyFarah Yasmin0Hala Najeeb1Hasan Fareed Siddiqui2Muhammad Sohaib Asghar3Hashir Ali Awan4Rana Muhammad Usama5Zoha Allahuddin6Muhammad Junaid Tahir7Kaleem Ullah8Mohammed Mahmmoud Fadelallah Eljack9Department of Medicine, Dow Medical College Dow University of Health Sciences Karachi PakistanDepartment of Medicine, Dow Medical College Dow University of Health Sciences Karachi PakistanDepartment of Medicine, Dow Medical College Dow University of Health Sciences Karachi PakistanDepartment of Medicine, Dow University Hospital‐Ojha Campus Dow University of Health Sciences Karachi PakistanDepartment of Medicine, Dow Medical College Dow University of Health Sciences Karachi PakistanDepartment of Medicine Lahore General Hospital Lahore PakistanDepartment of Medicine, Dow Medical College Dow University of Health Sciences Karachi PakistanDepartment of Radiology Pakistan Kidney and Liver Institute and Research Center (PKLI & RC) Lahore PakistanDepartment of Surgery, Liver Transplant and Hepatobiliary Unit Pir Abdul Qadir Shah Jelani Institute of Medical Sciences Gambat PakistanDepartment of Community Medicine, Faculty of Medicine and Health Sciences University of Bakht Alruda Ad Duwaym SudanAbstract Background Coronavirus disease 2019 (COVID‐19) vaccine side effects have an important role in the hesitancy of the general population toward vaccine administration. Therefore, this study was conducted to document the COVID‐19 vaccine side effects in our population. Materials and Methods An online survey‐based, cross‐sectional study was carried out from September 1, 2021, to October 1, 2021, to document the side effects of the COVID‐19 vaccine among the general public. The questionnaire included participants’ sociodemographic data, type of vaccine, comorbidities, previous COVID‐19 infection, and assessment of side effects reported by them. Results The majority of the participants were <20 years of age (62.2%), females (74.9%), belonged to the educational sector (58.1%), residents of Sindh (65.7%), and were previously unaffected by COVID‐19 infection (73.3%). Sinovac (38.7%) followed by Sinopharm (30.4%) and Moderna (18.4%) were administered more frequently. Commonly reported side effects were injection site pain (82%), myalgia (55%), headache (46%), fatigue/malaise (45%), and fever (41%). Vaccine side effects were more likely to be reported with the first dose as compared to the second dose. On regression analysis, factors associated with occurrence of side effects included younger age (odds ratio [OR]: 6.000 [2.065–17.431], p < 0.001), female gender (OR: 2.373 [1.146–4.914], p = 0.020), marital status (OR: 0.217 [0.085–0.556], p < 0.001), graduate level of education (OR: 0.353 [0.153–0.816], p = 0.015), and occupation being either retired, freelancers, or social workers (OR: 0.310 [0.106–0.909]), p = 0.033). Previous infection with COVID‐19 (p = 0.458) and comorbidities were found unrelated (p = 0.707) to the occurrence of side effects. Conclusion The overall prevalence of local side effects was quite higher than the systemic ones. Further large‐scale studies on vaccine safety are required to strengthen public confidence in the vaccination drive.https://doi.org/10.1002/hsr2.1071adverse effectsCOVID‐19 vaccinepostvaccination symptomsSARS‐CoV‐2 vaccinevaccine side effects |
| spellingShingle | Farah Yasmin Hala Najeeb Hasan Fareed Siddiqui Muhammad Sohaib Asghar Hashir Ali Awan Rana Muhammad Usama Zoha Allahuddin Muhammad Junaid Tahir Kaleem Ullah Mohammed Mahmmoud Fadelallah Eljack Frequency of COVID‐19 vaccine side effects and its associated factors among the vaccinated population of Pakistan: A cross‐sectional study Health Science Reports adverse effects COVID‐19 vaccine postvaccination symptoms SARS‐CoV‐2 vaccine vaccine side effects |
| title | Frequency of COVID‐19 vaccine side effects and its associated factors among the vaccinated population of Pakistan: A cross‐sectional study |
| title_full | Frequency of COVID‐19 vaccine side effects and its associated factors among the vaccinated population of Pakistan: A cross‐sectional study |
| title_fullStr | Frequency of COVID‐19 vaccine side effects and its associated factors among the vaccinated population of Pakistan: A cross‐sectional study |
| title_full_unstemmed | Frequency of COVID‐19 vaccine side effects and its associated factors among the vaccinated population of Pakistan: A cross‐sectional study |
| title_short | Frequency of COVID‐19 vaccine side effects and its associated factors among the vaccinated population of Pakistan: A cross‐sectional study |
| title_sort | frequency of covid 19 vaccine side effects and its associated factors among the vaccinated population of pakistan a cross sectional study |
| topic | adverse effects COVID‐19 vaccine postvaccination symptoms SARS‐CoV‐2 vaccine vaccine side effects |
| url | https://doi.org/10.1002/hsr2.1071 |
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