Mechanisms of Ca2+/calmodulin-dependent kinase II activation in single dendritic spines
Activation of Ca2+/calmodulin-dependent kinase II (CaMKII) in dendritic spines is a key step of long-term potentiation (LTP) induction, yet the exact biochemical steps of CaMKIIα activation in dendritic spines remained elusive. In this study, the authors developed a novel imaging approach to monitor...
Main Authors: | Jui-Yun Chang, Yoshihisa Nakahata, Yuki Hayano, Ryohei Yasuda |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2019-06-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-10694-z |
Similar Items
-
Dendritic spine changes in the development of alcohol addiction regulated by α-calcium/calmodulin-dependent protein kinase II
by: Zofia Mijakowska
Published: (2014-03-01) -
Inhibition of TRPP3 by calmodulin through Ca2+/calmodulin-dependent protein kinase II
by: Xiong Liu, et al.
Published: (2023-04-01) -
Plasticity of Spine Structure: Local Signaling, Translation and Cytoskeletal Reorganization
by: Yoshihisa Nakahata, et al.
Published: (2018-08-01) -
Control of Ca2+ Influx and Calmodulin Activation by SK-Channels in Dendritic Spines.
by: Thom Griffith, et al.
Published: (2016-05-01) -
A dynamic model of interactions of Ca2+, calmodulin, and catalytic subunits of Ca2+/calmodulin-dependent protein kinase II.
by: Shirley Pepke, et al.
Published: (2010-02-01)