Study on the effectiveness and safety of Foldable Capsular Vitreous Body implantation
Abstract Background Foldable capsular vitreous body (FCVB) was designed to treat severe retinal detachment. The aim of this study was to evaluate the efficacy and safety of the implantation of foldable capsular vitreous body in 1-year follow-up. Methods A retrospective analysis was conducted for 20...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-12-01
|
| Series: | BMC Ophthalmology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12886-019-1268-x |
| _version_ | 1819070528057507840 |
|---|---|
| author | Xiangyang Zhang Xuemin Tian Baike Zhang Lisa Guo Xiaodan Li Yong Jia |
| author_facet | Xiangyang Zhang Xuemin Tian Baike Zhang Lisa Guo Xiaodan Li Yong Jia |
| author_sort | Xiangyang Zhang |
| collection | DOAJ |
| description | Abstract Background Foldable capsular vitreous body (FCVB) was designed to treat severe retinal detachment. The aim of this study was to evaluate the efficacy and safety of the implantation of foldable capsular vitreous body in 1-year follow-up. Methods A retrospective analysis was conducted for 20 patients with severe ocular trauma or silicone oil (SO) dependent eyes underwent vitrectomy and FCVB implantation in a 1-year follow-up. All treated eyes were peformed clinical examinations involved the visual acuity (VA) examination, Goldmann applanation tonometer, noncontact specular microscopy, fundus photography, B-Scan examination and optical coherence tomography (OCT). The groups were compared with t-test and the McNemar - Bowker test. Results In 1-year follow-up, 20 eyes were evaluated in the study. FCVB well supported the vitreous retina in all treated eyes, and 6 treated eyes achieved retinal reattachment 12 months after FCVB implantation. There were no significant differences in VA before and after FCVB implantation (P = 1.000). In addition, the postoperative IOP markedly elevated from the preoperative IOP of 12.90 ± 7.06 mmHg to 15.15 ± 3.36 mmHg (P = 0.000017). The intraocular pressure (IOP) of 10 eyes maintained at a normal level after surgeries. The other 10 eyes showed slightly lower IOP within the acceptable level. Though two patients developed keratopathy and ocular inflammation respectively, other treated eyes were symmetric with fellow eyes showing satisfactory appearance. Moreover, there was no SO emulsification or leakage happened in the observation. Conclusions FCVB implantation was an effective and safe treatment in the eyes with severe retinal detachment. |
| first_indexed | 2024-12-21T17:07:22Z |
| format | Article |
| id | doaj.art-3596ad4603894bf5a59712e0bb0a06cf |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-21T17:07:22Z |
| publishDate | 2019-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-3596ad4603894bf5a59712e0bb0a06cf2022-12-21T18:56:30ZengBMCBMC Ophthalmology1471-24152019-12-011911910.1186/s12886-019-1268-xStudy on the effectiveness and safety of Foldable Capsular Vitreous Body implantationXiangyang Zhang0Xuemin Tian1Baike Zhang2Lisa Guo3Xiaodan Li4Yong Jia5Xinxiang Medical UniversityThe People’s Liberation Army 988th Hospital (formerly the People’s Liberation Army 153rd Hospital), No. 602 Zhengshang RoadThe People’s Liberation Army 988th Hospital (formerly the People’s Liberation Army 153rd Hospital), No. 602 Zhengshang RoadThe People’s Liberation Army 988th Hospital (formerly the People’s Liberation Army 153rd Hospital), No. 602 Zhengshang RoadThe People’s Liberation Army 988th Hospital (formerly the People’s Liberation Army 153rd Hospital), No. 602 Zhengshang RoadThe People’s Liberation Army 988th Hospital (formerly the People’s Liberation Army 153rd Hospital), No. 602 Zhengshang RoadAbstract Background Foldable capsular vitreous body (FCVB) was designed to treat severe retinal detachment. The aim of this study was to evaluate the efficacy and safety of the implantation of foldable capsular vitreous body in 1-year follow-up. Methods A retrospective analysis was conducted for 20 patients with severe ocular trauma or silicone oil (SO) dependent eyes underwent vitrectomy and FCVB implantation in a 1-year follow-up. All treated eyes were peformed clinical examinations involved the visual acuity (VA) examination, Goldmann applanation tonometer, noncontact specular microscopy, fundus photography, B-Scan examination and optical coherence tomography (OCT). The groups were compared with t-test and the McNemar - Bowker test. Results In 1-year follow-up, 20 eyes were evaluated in the study. FCVB well supported the vitreous retina in all treated eyes, and 6 treated eyes achieved retinal reattachment 12 months after FCVB implantation. There were no significant differences in VA before and after FCVB implantation (P = 1.000). In addition, the postoperative IOP markedly elevated from the preoperative IOP of 12.90 ± 7.06 mmHg to 15.15 ± 3.36 mmHg (P = 0.000017). The intraocular pressure (IOP) of 10 eyes maintained at a normal level after surgeries. The other 10 eyes showed slightly lower IOP within the acceptable level. Though two patients developed keratopathy and ocular inflammation respectively, other treated eyes were symmetric with fellow eyes showing satisfactory appearance. Moreover, there was no SO emulsification or leakage happened in the observation. Conclusions FCVB implantation was an effective and safe treatment in the eyes with severe retinal detachment.https://doi.org/10.1186/s12886-019-1268-xFoldable capsular vitreous bodyEfficacySafetyRetinal detachmentVitreoretinal diseaseVitrectomy |
| spellingShingle | Xiangyang Zhang Xuemin Tian Baike Zhang Lisa Guo Xiaodan Li Yong Jia Study on the effectiveness and safety of Foldable Capsular Vitreous Body implantation BMC Ophthalmology Foldable capsular vitreous body Efficacy Safety Retinal detachment Vitreoretinal disease Vitrectomy |
| title | Study on the effectiveness and safety of Foldable Capsular Vitreous Body implantation |
| title_full | Study on the effectiveness and safety of Foldable Capsular Vitreous Body implantation |
| title_fullStr | Study on the effectiveness and safety of Foldable Capsular Vitreous Body implantation |
| title_full_unstemmed | Study on the effectiveness and safety of Foldable Capsular Vitreous Body implantation |
| title_short | Study on the effectiveness and safety of Foldable Capsular Vitreous Body implantation |
| title_sort | study on the effectiveness and safety of foldable capsular vitreous body implantation |
| topic | Foldable capsular vitreous body Efficacy Safety Retinal detachment Vitreoretinal disease Vitrectomy |
| url | https://doi.org/10.1186/s12886-019-1268-x |
| work_keys_str_mv | AT xiangyangzhang studyontheeffectivenessandsafetyoffoldablecapsularvitreousbodyimplantation AT xuemintian studyontheeffectivenessandsafetyoffoldablecapsularvitreousbodyimplantation AT baikezhang studyontheeffectivenessandsafetyoffoldablecapsularvitreousbodyimplantation AT lisaguo studyontheeffectivenessandsafetyoffoldablecapsularvitreousbodyimplantation AT xiaodanli studyontheeffectivenessandsafetyoffoldablecapsularvitreousbodyimplantation AT yongjia studyontheeffectivenessandsafetyoffoldablecapsularvitreousbodyimplantation |